| Author | Barth, Ortrud Monika | |
| Author | Schatzmayr, Hermann G. | |
| Access date | 2020-09-19T16:48:12Z | |
| Available date | 2020-09-19T16:48:12Z | |
| Document date | 1992 | |
| Citation | BARTH, Ortrud Monika; SCHATZMAYR, Hermann G. Brazilian dengue virus type 1 replication in mosquito cell cultures. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 87, n. 1, p. 1-7, Jan./Mar. 1992. | pt_BR |
| ISSN | 0074-0206 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/43473 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Flaviviridae | pt_BR |
| Subject in Portuguese | Dengue tipo 1 | pt_BR |
| Subject in Portuguese | Ultraestrutura | pt_BR |
| Subject in Portuguese | Replicação de vírus | pt_BR |
| Title | Brazilian dengue virus type 1 replication in mosquito cell cultures | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02761992000100001 | |
| Abstract | he development of dengue viruses type 1 obtained from accute human sera and inoculated into mosquito cell cultures, was observed by standard transmission electron microscopy and cytochemical staining. It follows the trans-type mechanism already estabilished of other dengue types. Directed passage of single virus particles across the cell membrane seems to be a pathway of entry and exit in dengue-1 infected cells. The nature of numerous electron translucent vesicles and tubules, produced simmultaneously during virus replication inside the rough endoplasmic reticulum, was analyzed by cytochemical tests. The largest amount of virus particles was produced inside cell syncytia. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Flaviviridae | pt_BR |
| Subject | Dengue 1 | pt_BR |
| Subject | Virus replication | pt_BR |
| Subject | Ultrastructure | pt_BR |
| e-ISSN | 1678-8060 | |
