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AutorBorges, Juliano
AutorAraújo, Luciana
AutorCuzzi, Tullia
AutorMartinez, Luis
AutorGonzales, Yliana
AutorManela-Azulay, Mônica
Fecha de acceso2020-10-13T14:04:20Z
Fecha de disponibilización2020-10-13T14:04:20Z
Fecha de publicación2020
ReferenciaBORGES, Juliano et al. Fractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edema. The Journal of Clinical and Aesthetic Dermatology, v. 13, n. 1, p. 22-27, 2020.pt_BR
ISSN1941-2789pt_BR
xmlui.metadata.dc.identifier.otherPMID: 32082467
URIhttps://www.arca.fiocruz.br/handle/icict/43962
Idiomaengpt_BR
EditorMatrix Medical Communicationspt_BR
Derechos de autoropen accesspt_BR
TítuloFractional Laser Resurfacing Treats Photoaging by Promoting Neocollegenesis and Cutaneous Edemapt_BR
Tipo del documentoArticlept_BR
Resumen en InglésBACKGROUND: Laser resurfacing is a common treatment for photoaging. This treatment creates skin incisions that initiate the wound healing cascade, including reorganization of the collagen matrix, in a dermal remodeling process that can last up to 12 months. OBJECTIVE: We compared the effects of nonablative and ablative Erbium fractional laser resurfacing on dermal content and arrangement of Collagen Types I and III, and on fibroblast activation. METHODS: Ten female patients (50-63 years) with Fitzpatrick Skin Types I-IV and clinical signs of photoaging underwent two types of Erbium fractional laser resurfacing (nonablative, 1540nm; ablative, 2940nm) on opposite sides of the face. Skin biopsies were obtained pretreatment and three months post-treatment. Morphometric analysis was performed using Picrosirius staining for overall collagen, and immunohistochemistry for Collagen Types I and III. Finally, hematoxylin and eosin staining was used to identify fibroblast activation. RESULTS: Both laser treatments induced reorganization of Collagen Types I and III and demonstrated signs of fibroblast activation. However, morphometric analysis of Picrosirius staining revealed that, after both treatments, there was a lower density of collagen fibers, which is characteristic of edema. CONCLUSION: At three months after laser resurfacing, skin lifting in photoaged skin likely resulted from new collagen deposition but also from edema.pt_BR
AfiliaciónUniversidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónUniversidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónSanta Casa de Misericórdia do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónSanta Casa de Misericórdia do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.pt_BR
AfiliaciónUniversidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.pt_BR
Palavras clave en InglêsCollagen Type Ipt_BR
Palavras clave en InglêsCollagen Type IIIpt_BR
Palavras clave en InglêsErbium fractional laser resurfacingpt_BR
Palavras clave en InglêsAblativept_BR
Palavras clave en InglêsAging skinpt_BR
Palavras clave en InglêsNonablativept_BR
Palavras clave en InglêsPhotoagingpt_BR
Palavras clave en InglêsRejuvenationpt_BR
Palavras clave en InglêsSolar elastosispt_BR
xmlui.metadata.dc.subject.ods07 Energia limpa e acessível


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