| Author | Conceição, Maria José | |
| Author | Argento, Carlos Alberto | |
| Author | Corrêa, Acyr | |
| Access date | 2020-10-19T18:19:08Z | |
| Available date | 2020-10-19T18:19:08Z | |
| Document date | 2000 | |
| Citation | CONCEIÇÃO, Maria José; ARGENTO, Carlos Alberto; CORRÊA, Acyr. Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95, n. 3, p. 375-380, May/June 2000. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44064 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Schistosoma mansoni | pt_BR |
| Subject in Portuguese | Pacientes | pt_BR |
| Subject in Portuguese | Oxamniquine | pt_BR |
| Subject in Portuguese | Failure of treatment | pt_BR |
| Title | Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02762000000300013 | |
| Abstract | After three successive treatments with oxamniquine the continuing elimination of Schistosoma mansoni
eggs was observed in patients, who came from various regions of Brazil, with different clinical forms of
schistosomiasis. The objective of the present study was to determine the experimental behaviour of five
different S. mansoni isolates in Swiss Webster mice that were submitted to treatment with the same drug.
The experimental group with failure of treatment showed higher mean number of surviving male worms
when it was compared to the group without failure of treatment. These date suggest the possibility of
resistance to oxamniquine. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Departamento de Medicina Preventiva. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Schistosoma mansoni | pt_BR |
| Subject | Patients | pt_BR |
| Subject | Oxamniquine | pt_BR |
| Subject | Failure of treatment | pt_BR |
| e-ISSN | 1678-8060 | |
