| Author | McNett, Molly | |
| Author | Fink, Ericka L. | |
| Author | Schober, Michelle | |
| Author | Mainali, Shraddha | |
| Author | Helbok, Raimund | |
| Author | Robertson, Courtney L. | |
| Author | Mejia-Mantilla, Jorge | |
| Author | Kurtz, Pedro | |
| Author | Righy, Cássia | |
| Author | Roa, Juan D. | |
| Author | Villamizar-Rosales, Carlos | |
| Author | Altamirano, Valeria | |
| Author | Frontera, Jennifer A. | |
| Author | Maldonado, Nelson | |
| Author | Menon, David | |
| Author | Suarez, Jose | |
| Author | Chou, Sherry H. Y. | |
| Access date | 2020-10-20T00:30:38Z | |
| Available date | 2020-10-20T00:30:38Z | |
| Document date | 2020 | |
| Citation | MCNETT, Molly et al. The Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Development of Case Report Forms for Global Use. Neurocritical Care, v. 33, n. 3, p. 793-828, Dec. 2020. | pt_BR |
| ISSN | 1541-6933 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44073 | |
| Sponsorship | This publication was supported by the National Institutes of Health (NIH), National Center for Advancing Translational Sciences (NCATS) through Grant Number(s) UL1 TR001857 (University of Pittsburgh/Chou), the National Institute of Health (R21NS113037, Chou), the University of Pittsburgh Dean’s Faculty Advancement Award (Chou). | |
| Language | eng | pt_BR |
| Publisher | Springer | pt_BR |
| Rights | open access | pt_BR |
| Title | The Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Development of Case Report Forms for Global Use | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1007/s12028-020-01100-4 | |
| Abstract | Since its original report in January 2020, the coronavirus disease 2019 (COVID-19) due to Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infection has rapidly become one of the deadliest global pandemics. Early reports indicate possible neurological manifestations associated with COVID-19, with symptoms ranging from mild to severe, highly variable prevalence rates, and uncertainty regarding causal or coincidental occurrence of symptoms. As neurological involvement of any systemic disease is frequently associated with adverse effects on morbidity and mortality, obtaining accurate and consistent global data on the extent to which COVID-19 may impact the nervous system is urgently needed. To address this need, investigators from the Neurocritical Care Society launched the Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID). The GCS-NeuroCOVID consortium rapidly implemented a Tier 1, pragmatic study to establish phenotypes and prevalence of neurological manifestations of COVID-19. A key component of this global collaboration is development and application of common data elements (CDEs) and definitions to facilitate rigorous and systematic data collection across resource settings. Integration of these elements is critical to reduce heterogeneity of data and allow for future high-quality meta-analyses. The GCS-NeuroCOVID consortium specifically designed these elements to be feasible for clinician investigators during a global pandemic when healthcare systems are likely overwhelmed and resources for research may be limited. Elements include pediatric components and translated versions to facilitate collaboration and data capture in Latin America, one of the epicenters of this global outbreak. In this manuscript, we share the specific data elements, definitions, and rationale for the adult and pediatric CDEs for Tier 1 of the GCS-NeuroCOVID consortium, as well as the translated versions adapted for use in Latin America. Global efforts are underway to further harmonize CDEs with other large consortia studying neurological and general aspects of COVID-19 infections. Ultimately, the GCS-NeuroCOVID consortium network provides a critical infrastructure to systematically capture data in current and future unanticipated disasters and disease outbreaks. | pt_BR |
| Affilliation | The Ohio State University. College of Nursing. Columbus, OH, USA. | pt_BR |
| Affilliation | UPMC Children's Hospital of Pittsburgh. Division of Pediatric Critical Care Medicine and Safar Center for Resuscitation Research. Pittsburgh, PA, USA. | pt_BR |
| Affilliation | University of Utah School of Medicine. Primary Children's Hospital. Salt Lake City, UT, USA. | pt_BR |
| Affilliation | The Ohio State University. Department of Neurology. Division of Stroke and Neurocritical Care. Columbus, OH, USA. | pt_BR |
| Affilliation | Medical University of Innsbruck. Department of Neurology. Neurocritical Care Unit. Innsbruck, Austria. | pt_BR |
| Affilliation | Johns Hopkins Children's Center. The Johns Hopkins University SOM. Departments of Anesthesiology and Critical Care Medicine, and Pediatrics. Baltimore, MD, USA. | pt_BR |
| Affilliation | University Hospital. Fundacio Valle del Lili. Department of Neuro-Intensive Care and Anesthesiology. Cali, Colombia. | pt_BR |
| Affilliation | Paulo Niemeyer State Brain Institute. Rio de Janeiro, RJ, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidad Nacional de Colombia. Fundación Universitaria de Ciencias de la Salud. Department of Pediatric Neurology and Critical Care. Bogotá, Colombia. | pt_BR |
| Affilliation | The University of Pittsburgh Medical Center. Pittsburgh, PA, USA. | pt_BR |
| Affilliation | The University of Pittsburgh Medical Center. Pittsburgh, PA, USA. | pt_BR |
| Affilliation | NYU Grossman School of Medicine. Department of Neurology. New York, NY, USA. | pt_BR |
| Affilliation | Universidad San Francisco de Quito. Department of Neurology de los Valles. Quito, Ecuador. | pt_BR |
| Affilliation | Addenbrooke's Hospital Cambridge. University of Cambridge. Division of Anaesthesia. Cambridge, UK. | pt_BR |
| Affilliation | The Johns Hopkins University School of Medicine. Departments of Anesthesiology and Critical Care Medicine, Neurology, and Neurosurgery. Baltimore, MD, USA. | pt_BR |
| Affilliation | Safar Center for Resuscitation Research. University of Pittsburgh School of Medicine. Departments of Critical Care Medicine, Neurology, and Neurosurgery. Pittsburgh, PA, USA. | pt_BR |
| Subject | COVID-19 | pt_BR |
| Subject | Case report form | pt_BR |
| Subject | Common data element | pt_BR |
| Subject | Coronavirus | pt_BR |
| Subject | Disease prevalence | pt_BR |
| Subject | Neurological manifestations | pt_BR |
| Subject | Neurological symptoms | pt_BR |
| Subject | SARS-CoV-2 | pt_BR |
| e-ISSN | 1556-0961 | |
