| Author | Trinta, Karen S. | |
| Author | Liberto, Maria Isabel M. | |
| Author | Paula, Vanessa S. de | |
| Author | Yoshida, Clara F. T. | |
| Author | Gaspar, Ana M. C. | |
| Access date | 2020-10-21T19:46:40Z | |
| Available date | 2020-10-21T19:46:40Z | |
| Document date | 2001 | |
| Citation | TRINTA, Karen S, et al. Hepatitis E Virus Infection in Selected Brazilian Populations. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 96, n. 1, p. 25-29, Jan. 2001. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44108 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Vírus da Hepatite E | pt_BR |
| Subject in Portuguese | Vírus de Hapatite A | pt_BR |
| Subject in Portuguese | Soroepidemiologia | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Hepatitis E Virus Infection in Selected Brazilian Populations | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02762001000100004 | |
| Abstract | A retrospective study on the prevalence of hepatitis E virus (HEV) infection was conducted in
selected populations in Rio de Janeiro, Brazil. A total of 1,115 subjects were tested including 146
patients with acute Non-A Non-B Non-C (NANBNC) viral hepatitis, 65 hemodialysis patients, 93 blood
donors, 102 intravenous drug users (IVDUs), 304 pregnant women, 145 individuals living in the rural
area and 260 individuals living in the urban area. In order to characterize a favorable epidemiological
set for enterically transmitted infection in the studied populations we also evaluated the prevalence of
anti-HAV IgG (hepatitis A virus) antibodies. Specific antibodies to HEV (anti-HEV IgG) were detected
by a commercial EIA and specific antibodies to HAV (anti-HAV IgG) were detected using a competitive
“in house” EIA. We found a high prevalence of anti-HAV IgG in these populations, that could indicate
some risk for infections transmitted via the fecal-oral route. The anti-HEV IgG prevalence among the
different groups were: 2.1% in patients with acute NANBNC viral hepatitis, 6.2% in hemodialysis
patients, 4.3% in blood donors, 11.8% in IVDUs, 1% in pregnant women, and 2.1% in individuals form
the rural area. Among individuals living in the urban area we did not find a single positive serum
sample. Our results demonstrated the presence of anti-HEV IgG in almost all studied populations;
however, further studies are necessary to establish the real situation of HEV epidemiology in Rio de
Janeiro, Brazil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Prof. Paulo de Góes. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Hepatitis E virus | pt_BR |
| Subject | Hepatitis A virus | pt_BR |
| Subject | Seroepidemiology | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
| Subject | Brazil | pt_BR |
| e-ISSN | 1678-8060 | |
