| Author | Santos, Damião Carlos Moraes dos | |
| Author | Souto, Francisco José Dutra | |
| Author | Santos, Débora Regina Lopes dos | |
| Author | Vitral, Cláudia Lamarca | |
| Author | Gaspar, Ana Maria Coimbra | |
| Access date | 2020-10-26T13:19:32Z | |
| Available date | 2020-10-26T13:19:32Z | |
| Document date | 2002 | |
| Citation | SANTOS, Damião Carlos Moraes dos et al. Seroepidemiological Markers of Enterically Transmitted Viral Hepatitis A and E in Individuals Living in a Community Located in the North Area of Rio de Janeiro, RJ, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 5, p. 637-640, July 2002. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44188 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Vírus da Hepatite A | pt_BR |
| Subject in Portuguese | Vírus da Hepatite E | pt_BR |
| Subject in Portuguese | Soroprevalência | pt_BR |
| Subject in Portuguese | Epidemiologia | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Title | Seroepidemiological Markers of Enterically Transmitted Viral Hepatitis A and E in Individuals Living in a Community Located in the North Area of Rio de Janeiro, RJ, Brazil | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/S0074-02762002000500007 | |
| Abstract | We investigated the seroprevalence of hepatitis A virus (HAV) and hepatitis E virus (HEV) infection in subjects
living in the community of Manguinhos, Rio de Janeiro, Brazil, and assisted at the Health Unit of Escola Nacional
de Saúde Pública, Fundação Oswaldo Cruz. After formal consent, individuals were submitted to an interview using
a standardized questionnaire. Anti-HAV and anti-HEV antibodies were detected by ELISA. Statistical analysis was
carried out using the Epi-Info 6.04b software, to investigate possible associations between serological markers and
risk factors. Results were regarded as significant when p value < 0.05.
Although a high prevalence of anti-HAV was observed (87%), almost 50% of subjects under the age of 10 were
susceptible to HAV infection, an unexpected rate in endemic areas. This fact could be attributed to improvements in
environmental sanitation, occurring in this area in the last years. The increasing proportion of susceptible people
may result in outbreaks of HAV infection, since the virus still circulates in this area, as verified by the detection of
anti-HAV IgM in some individuals. No statistical association was met between HAV infection and the risk factors
here assessed. The anti-HEV IgG prevalence found in this population was 2.4%, consistent with the one found in
non-endemic areas. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Universidade Federal do Mato Grosso, Cuiabá, MT, BrasiL. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Niterói, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Hepatitis A virus | pt_BR |
| Subject | Hepatitis E virus | pt_BR |
| Subject | Seroprevalence | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
| Subject | Brazil | pt_BR |
| e-ISSN | 1678-8060 | |
