| Author | Macedo, Priscila Marques de | |
| Author | Scramignon-Costa, Bruno de Souza | |
| Author | Almeida-Paes, Rodrigo | |
| Author | Trilles, Luciana | |
| Author | Oliveira, Larissa Siston Cosendey de | |
| Author | Zancopé-Oliveira, Rosely Maria | |
| Author | Valle, Antonio Carlos Francesconi do | |
| Author | Wanke, Bodo | |
| Access date | 2020-10-28T15:02:17Z | |
| Available date | 2020-10-28T15:02:17Z | |
| Document date | 2020 | |
| Citation | MACEDO, Priscila Marques et al. Paracoccidioides brasiliensis habitat: far beyond armadillo burrows? Memórias do Instituto Oswaldo Cruz, v. 115, p. 1-3, 2020 | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44253 | |
| Language | eng | pt_BR |
| Publisher | Scielo | pt_BR |
| Rights | open access | pt_BR |
| Title | Paracoccidioides brasiliensis habitat: far beyond armadillo burrows? | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/0074-02760200208 | |
| Abstract | Paracoccidioides spp. isolation from environmental samples is rare and hardly reproducible. Molecular techniques have facilitated the fungal detection. However, it can be still difficult. Some strategies to enhance the capacity of DNA detection have been adopted, including the analysis of soil samples belonging to the habitat of animals from which Paracoccidioides spp. have already been isolated, notably armadillo burrows. To date, the detection of Paracoccidioides spp. has not yet been reported from outbreak hotspots. Clusters and outbreaks of acute paracoccidioidomycosis (PCM), usually a more severe clinical form, have currently occurred in urban areas being associated to climate changes, deforestation, and great constructions. These occurrences potentially signalise the fungus’ environmental niche, a riddle not yet solved. The authors performed an environmental investigation in a deeply disturbed area, after a highway construction in Rio de Janeiro, Brazil, where a recent outbreak of acute PCM occurred. Specific DNA sequences of Paracoccidioides brasiliensis were detected in shallow soil samples around the highway, reinforcing the association between the road construction and this PCM outbreak. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Outbreak | pt_BR |
| Subject | Environment | pt_BR |
| Subject | Paracoccidioidomycosis | pt_BR |
| Subject | Paracoccidioides brasiliensis | pt_BR |
