| Author | Oelemann, Maraníbia C. | |
| Author | Fontes, Amanda N. B. | |
| Author | Pereira, Marcia A. da Silva | |
| Author | Bravin, Yolanda | |
| Author | Silva, Guida | |
| Author | Degrave, Win | |
| Author | Carvalho, Anna Cristina | |
| Author | Brito, Rossana | |
| Author | Kritski, Afrânio L. | |
| Author | Suffys, Philip N. | |
| Access date | 2020-11-22T19:11:30Z | |
| Available date | 2020-11-22T19:11:30Z | |
| Document date | 2007 | |
| Citation | OELEMANN, Maraníbia C. et al. Typing of Mycobacterium tuberculosis strains isolated in Community Health Centers of Rio de Janeiro City, Brazil. Memórias do Instituto 0swaldo Cruz, Rio de Janeiro, v. 102, n. 4, p. 455-462, June 2007. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44576 | |
| Language | eng | pt_BR |
| Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Tuberculose | pt_BR |
| Subject in Portuguese | Elemento duplo repetitivo | pt_BR |
| Subject in Portuguese | Epidemiologia molecular | pt_BR |
| Subject in Portuguese | Polimorfismo de comprimento de fragmento de restrição IS6110 | pt_BR |
| Title | Typing of Mycobacterium tuberculosis strains isolated in Community Health Centers of Rio de Janeiro City, Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1590/S0074-02762007005000034 | |
| Abstract | Fingerprinting of Mycobacterium tuberculosis strains from tuberculosis (TB) patients attended in Community Health Centers (CHCs) of Rio de Janeiro was performed to verify possible risk factors for TB transmission.
A prospective community-based study was performed during the period of July 1996 to December 1996 by
collecting sputum samples of 489 patients in 11 different CHCs in four different planning areas (APs) of the city.
Bacteriological, clinical, and epidemiological information was collected and M. tuberculosis genotypes defined after restriction fragment length polymorphism (IS6110-RFLP) and double repetitive element (DRE) fingerprinting of RFLP-clustered cases. Risk factors for TB transmission were looked for using three levels of
cluster stringency. Among 349 (71%) positive cultures obtained, IS6110-RFLP typing could be performed on
strains from 153 different patients. When using identity of RFLP patterns as cluster definition, 49 (32%) of the
strains belonged to a cluster and none of the clinical or epidemiologic characteristics was associated with
higher clustering levels. However, higher clustering level was observed in the AP including the central region
of the city when compared to others. This strongly suggests that more recent transmission occurs in that area
and this may be related with higher incidence of TB and HIV in this region. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micobacterioses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micobacterioses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micobacterioses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Laboratório Central Noel Nutels. Rio de Janeiro RJ, Brasil. | pt_BR |
| Affilliation | Secretaria Municipal de Saúde do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micobacterioses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Programa Acadêmico em Tuberculose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Programa Acadêmico em Tuberculose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Programa Acadêmico em Tuberculose. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micobacterioses. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Tuberculosis | pt_BR |
| Subject | Molecular epidemiology | pt_BR |
| Subject | IS6110-restriction fragment length polymorphism | pt_BR |
| Subject | Double repetitive element | pt_BR |
| e-ISSN | 1678-8060 | |
