| Author | Nascimento, Israel Júnior Borges do | |
| Author | Pinto, Luiz Ricardo | |
| Author | Fernandes, Valéria Alves | |
| Author | Romero, Israel Molina | |
| Author | Oliveira, João Antonio de Queiroz | |
| Author | Marcolino, Milena Soriano | |
| Author | Leite, Maria Fátima | |
| Access date | 2020-12-07T13:16:17Z | |
| Available date | 2020-12-07T13:16:17Z | |
| Document date | 2020 | |
| Citation | NASCIMENTO, Israel Júnior Borges do et al. Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study. São Paulo Medical Journal, p. 1-8, 2020. | pt_BR |
| ISSN | 1516-3180 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/44726 | |
| Language | eng | pt_BR |
| Publisher | Associação Paulista de Medicina | pt_BR |
| Rights | open access | pt_BR |
| Title | Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/1516-3180.2020.00365.r1.08092020 | |
| Abstract | BACKGROUND: Since February 2020, data on the clinical features of patients infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their clinical evolution have been gathered and intensively discussed, especially in countries with dramatic dissemination of this disease. OBJECTIVE: To assess the clinical features of Brazilian patients with SARS-CoV-2 and analyze its local epidemiological features. DESIGN AND SETTING: Observational retrospective study conducted using data from an official electronic platform for recording confirmed SARS-CoV-2 cases. METHODS: We extracted data from patients based in the state of Pernambuco who were registered on the platform of the Center for Strategic Health Surveillance Information, between February 26 and May 25, 2020. Clinical signs/symptoms, case evolution over time, distribution of confirmed, recovered and fatal cases and relationship between age group and gender were assessed. RESULTS: We included 28,854 patients who were positive for SARS-CoV-2 (56.13% females), of median age 44.18 years. SARS-CoV-2 infection was most frequent among adults aged 30-39 years. Among cases that progressed to death, the most frequent age range was 70-79 years. Overall, the mortality rate in the cohort was 8.06%; recovery rate, 30.7%; and hospital admission rate (up to the end of follow-up), 17.3%. The average length of time between symptom onset and death was 10.3 days. The most commonly reported symptoms were coughing (42.39%), fever (38.03%) and dyspnea/respiratory distress with oxygen saturation < 95% (30.98%). CONCLUSION: Coughing, fever and dyspnea/respiratory distress with oxygen saturation < 95% were the commonest symptoms. The case-fatality rate was 8.06% and the hospitalization rate, 17.3%. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Clinical Pathologist and Medical Research Specialist. University Hospital and School of Medicine. Belo Horizonte, MG, Brazil / Medical Research Specialist. School of Medicine. Medical College of Wisconsin. Milwaukee, Wisconsin, USA. | pt_BR |
| Affilliation | Department of Production Engineering, School of Engineering, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | University Hospital and School of Medicine. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Department of Infectious Diseases. Vall d’Hebron Hospital. Barcelona, Spain / Oswaldo Cruz Foundation. Instituto Renê Rachou. Medical Researcher. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | University Hospital and School of Medicin. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | University Hospital and School of Medicine. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Department of Physiology and Biophysics. Institute of Biological Science. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil. | pt_BR |
| Subject | SARS-CoV-2 | pt_BR |
| Subject | COVID-19 | pt_BR |
| Subject | Coronavirus infections | pt_BR |
| Subject | Mandatory reporting | pt_BR |
| Subject | Public reporting of healthcare data | pt_BR |
| Subject | Infectious diseases | pt_BR |
| Subject | Novel coronavirus | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
