| Author | Paula, Vanessa Salete de | |
| Author | Milagres, Flavio Augusto Pádua | |
| Author | Oliveira, Guilherme de Macêdo | |
| Author | Miguel, Juliana Custódio | |
| Author | Cruz, Helena Medina | |
| Author | Scaloni, Letícia de Paula | |
| Author | Maques, Vanessa Alves | |
| Author | Magalhães, Monica de Avelar Figueiredo Mafra | |
| Author | Romão, Anselmo Rocha | |
| Author | Gracie, Renata | |
| Author | Villar, Livia Melo | |
| Access date | 2020-12-27T18:57:44Z | |
| Available date | 2020-12-27T18:57:44Z | |
| Document date | 2020 | |
| Citation | PAULA, Vanessa Salete de et al. High prevalence of hepatitis A in indigenous population in north Brazil. BMC Research Notes, v. 13, n. 458, p. 1-7, 2020. | en_US |
| ISSN | 1756-0500 | |
| URI | https://www.arca.fiocruz.br/handle/icict/45440 | |
| Language | eng | en_US |
| Publisher | BMC | en_US |
| Rights | open access | |
| Subject in Portuguese | Alta prevalência | en_US |
| Subject in Portuguese | Hepatite A | en_US |
| Subject in Portuguese | População indígena | en_US |
| Subject in Portuguese | Norte do Brasil | en_US |
| Title | High prevalence of hepatitis A in indigenous population on north Brazil | en_US |
| Type | Article | |
| DOI | 10.1186/s13104-020-05303-y | |
| Abstract | Objectives: Little is known about hepatitis A virus (HAV) prevalence in indigenous communities. This study aims to evaluate the prevalence of HAV in indigenous community compared to urban population located at Western Amazon in Brazil. Results: A total of 872 serum samples were obtained from 491 indigenous and 381 non indigenous individuals aging 0 to 90 years. Samples were tested for total and IgM anti-HAV and positive IgM samples were tested for HAV RNA. The overall prevalence of total anti-HAV was 87%, increased according age showing 100% of prevalence in those aging more than 30 years (p<0.0001) and it was similar among indigenous and urban population. Total anti-HAV prevalence varied between tribes (p<0.0001) and urban sites (p=0.0014) and spatial distribution showed high prevalence in homes that received up to 100 dollars. IgM anti-HAV prevalence was 1.7% with predominance in males, those aging more than 41 years. No HAV RNA was detected. In conclusion, high overall anti-HAV prevalence was found in indigenous communities in North Brazil demonstrating the importance of universal vaccination in this group. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Universidade Federal de Tocantins. Tocantins, Brasil. | en_US |
| Affilliation | Instituto Nacional de Cãncer. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil / University of Plymouth. Hepatology Research Group..Plymouth, Devon, UK. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Laboratório de Informação em Sáude. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Laboratório de Informação em Sáude. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Laboratório de Informação em Sáude. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Subject | High prevalence | en_US |
| Subject | Hepatitis A | en_US |
| Subject | Indigenous population | en_US |
| Subject | North Brazil | en_US |
| xmlui.metadata.dc.subject.ods | 16 Paz, Justiça e Instituições Eficazes | |
