| Author | Ferreira Junior, Paulo Antonio | |
| Author | Oliveira, Elaine Cristina de | |
| Author | Martin, Thamires Oliveira Gasquez | |
| Author | Alves Junior, Eduardo Rodrigues | |
| Author | Silva, Lucas José da | |
| Author | Mello, Francisco Campello do Amaral | |
| Author | Fontes, Cor Jesus Fernandes | |
| Author | Souto, Francisco José Dutra | |
| Access date | 2020-12-28T14:30:44Z | |
| Available date | 2020-12-28T14:30:44Z | |
| Document date | 2020 | |
| Citation | FERREIRA JUNIOR, Paulo Antonio et al. Prevalence of hepatitis B and D virus infection in a district of Mato Grosso, bordering Amazonas and Rondônia states. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 53, p. 1-7, Oct. 2020. | pt_BR |
| ISSN | 0037-8682 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/45442 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Hepatite B | pt_BR |
| Subject in Portuguese | Prevalência | pt_BR |
| Subject in Portuguese | Hepatite D | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Subject in Portuguese | Amazônia | pt_BR |
| Subject in Portuguese | Pesquisa | pt_BR |
| Title | Prevalence of hepatitis B and D virus infection in a district of Mato Grosso, bordering Amazonas and Rondônia states | pt_BR |
| Type | Article | |
| DOI | 10.1590/0037-8682-0559-2019 | |
| Abstract | Introduction: Brazil’s western Amazon basin has the highest prevalence of hepatitis B virus (HBV) infection in the country. Coinfection with hepatitis D virus (HDV) is also endemic. To estimate the prevalence of HBV and HDV markers in a population inhabiting the northwest portion of Mato Grosso state in the western Amazon. Methods: We performed a cross-sectional study of the seroprevalence of antibodies against HBV core antigen (anti-HBc) in the Três Fronteiras District northwest of Mato Grosso. Anti-HBc-positive subjects were tested for HBV surface antigen (HBsAg). Those positive for this marker were tested for HDV antibodies. Anti-HBc-negative participants were tested for anti-HBsAg. All tests were performed by EIA. Results: A total of 623 individuals in the community were assessed; the majority (67.6%) were male, with a mean age of 30.8 ± 15.4 years. Two hundred and fourteen individuals (34.3%) were anti-HBc-positive, and 47 (7.5%) were HBsAg carriers. Only one individual was anti-HDV-positive. Among the 409 individuals without HBV infection, 18.3% were anti-HBsAg-positive. There was no association between HBV infection and known risk factors. Conclusions: The study area had intermediate-to-high endemicity for HBV infection, but a low prevalence of HDV. Our serological results suggesting low vaccinationinduced protection indicate a need for reinforced immunization programs in the populations of northwest Mato Grosso. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil / Secretaria de Estado de Saúde de Mato Grosso. Superintendência de Vigilância em Saúde. Coordenação de Vigilância Epidemiológica. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil / Secretaria de Estado de Saúde de Mato Grosso. Superintendência de Vigilância em Saúde. Coordenação de Vigilância Epidemiológica. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso. Faculdade de Medicina. Hospital Universitário Júlio Müller. Cuiabá, MT, Brasil. | pt_BR |
| Subject | Hepatitis B | pt_BR |
| Subject | Prevalence | pt_BR |
| Subject | Hepatitis D | pt_BR |
| Subject | Amazon | pt_BR |
| Subject | Survey | pt_BR |
| e-ISSN | 1678-9849 | |
