| Author | Caetano, Karlla A. A. | |
| Author | Bergamaschi, Fabiana P. R. | |
| Author | Carneiro, Megmar A. S. Carneiro | |
| Author | Pinheiro, Raquel S. | |
| Author | Araújo, Lyriane A. | |
| Author | Matos, Marcos A. | |
| Author | Carvalho, Paulie M. R. S. | |
| Author | Souza, Márcia M. de | |
| Author | Matos, Márcia A. D. de | |
| Author | Del-Rios, Nativa Helena A. | |
| Author | Martins, Regina M. B. | |
| Author | Motto-Castro, Ana Rita C. | |
| Author | Soares, Caroline C. | |
| Author | Cook, Robert L. | |
| Author | Teles, Sheila A. | |
| Access date | 2021-01-14T18:33:50Z | |
| Available date | 2021-01-14T18:33:50Z | |
| Document date | 2020 | |
| Citation | CAETANO, Karila A. A. et al. Hepatotropic viruses (hepatitis A, B, C, D and E) in a rural Brazilian population: prevalence, genotypes, risk factors and vaccination. Trans R Soc Trop Med Hyg, v. 114, p. 91-98, 2020. | pt_BR |
| ISSN | 0035-9203 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/45706 | |
| Language | eng | pt_BR |
| Publisher | Oxford University Press | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Epidemiologia | pt_BR |
| Subject in Portuguese | Vacinas contra hepatite B humana | pt_BR |
| Subject in Portuguese | Hepatite | pt_BR |
| Subject in Portuguese | Fatores de risco | pt_BR |
| Subject in Portuguese | Viral | pt_BR |
| Title | Hepatotropic viruses (hepatitis A, B, C, D and E) in a rural Brazilian population: prevalence, genotypes, risk factors and vaccination | pt_BR |
| Type | Article | |
| DOI | 10.1093/trstmh/trz080 | |
| Abstract | Background: People living in settlement projects represent an emergent rural population in Brazil. Data on
their health is scarce and there are no data on viral hepatitis in this population. This study investigated the
epidemiology of viral hepatitis A-E in residents of settlement projects in central Brazil.
Methods: During 2011 and 2012, 923 people living in rural settlements in central Brazil were interviewed and
tested to estimate the prevalence of exposure to viral hepatitis A-E, to identify the circulating hepatitis B virus
(HBV)/hepatitis C virus (HCV) genotypes and risk factors for HBV exposure and to evaluate adherence to the
hepatitis B vaccination series.
Results: Overall, 85.9, 3.9, 0.4 and 17.3% of individuals showed evidence of exposure to hepatitis A virus (HAV),
hepatitis E virus, HCV and HBV, respectively. Among HBV-DNA positive samples (n=8), subgenotypes A1 (n=3)
and A2 (n=1) and genotype D/subgenotype D3 (n=4) were identified. Hepatitis D virus superinfection was
detected in 0/16 HBsAg-positive participants. A total of 229 individuals showed serological evidence of HBV
vaccination. In total, 442 settlers were eligible for vaccination, but only 150 individuals completed the vaccine
series. All anti-HCV-positive samples (n=4) were also HCV-RNA positive and identified as subtype 1a.
Conclusions: The intermediate endemicity of HAV, the higher prevalence of HBV exposure compared with urban
areas and the low compliance with HBV vaccination requires preventive measures focused on rural populations,
emphasizing the need for HAV and HBV vaccination. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade do Estado de Mato Grosso do Sul. Faculdade de Enfermagem. Dourados, MS, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, Go, Brasil. | pt_BR |
| Affilliation | Instituto Federal de Educação, Ciência e Tecnologia de Goiás. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Instituto Federal de Educação, Ciência e Tecnologia de Goiás. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, Go, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, Go, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, Go, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Mato Grosso do Sul. Centro para Ciências Biológicas e da Saúde, Campo Grande, MS, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Melecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | University of Florida. College of Public Health and Health Professions and College of Medicine. Department of Epidemiology,. Gainesville, FL. USA. | pt_BR |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Goiânia, GO, Brasil. | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject | Hepatitis | pt_BR |
| Subject | Human hepatitis B vaccines | pt_BR |
| Subject | RIsk factors | pt_BR |
| Subject | Viral | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
