| Author | Brandão, Elida M. V. | |
| Author | Xavier, Samanta C. C. | |
| Author | Rocha, Fabiana L. | |
| Author | LIma, Caio F. M. | |
| Author | Candeias, Ísis Z. | |
| Author | Lemos, Frederico G. | |
| Author | Azevedo, Fernanda C. | |
| Author | Jansen, Ana Maria | |
| Author | Roque, André L. R. | |
| Access date | 2021-01-26T14:57:43Z | |
| Available date | 2021-01-26T14:57:43Z | |
| Document date | 2020 | |
| Citation | BRANDÃO, Elida M. V. et al. Wild and Domestic Canids and Their Interactions in the Transmission Cycles of Trypanosoma Cruzi and Leishmania spp. in an Area of the Brazilian Cerrado. Pathogens, v. 9, n. 818, 19p, 2020. | pt_BR |
| ISSN | 2076-0817 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/45828 | |
| Language | eng | pt_BR |
| Publisher | MDPI | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Lycalopex vetulus | pt_BR |
| Subject in Portuguese | Cerdocyon thous | pt_BR |
| Subject in Portuguese | Chrysocyon brachyurus | pt_BR |
| Subject in Portuguese | Canis lupus familiaris | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Leishmania spp | pt_BR |
| Subject in Portuguese | Cerrado | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Subject in Portuguese | Mamíferos neotropicais | pt_BR |
| Title | Wild and Domestic Canids and Their Interactions in the Transmission Cycles of Trypanosoma Cruzi and Leishmania spp. in an Area of the Brazilian Cerrado | pt_BR |
| Type | Article | |
| DOI | 10.3390/pathogens9100818 | |
| Abstract | Trypanosoma cruzi and Leishmania spp. are parasites that infect multiple hosts including
canids, considered bioaccumulators of parasites. Deforestation in the Cerrado biome has resulted in the
exposure of wild canids to anthropized areas, where they may establish ecological and epidemiological
relationships with domestic dogs. We evaluated the infection by trypanosomatids in canids from a
Cerrado agroecosystem between 2013 and 2017. Samples of wild canids (blood, bone marrow and
skin) and dogs (blood) were collected for parasitological, serological and molecular diagnosis. A total
of 414 samples from wild (n = 131) and domestic (n = 283) canids were collected, including recaptures.
We obtained five positive hemocultures from Lycalopex vetulus (n = 2), Cerdocyon thous (n = 1) and
dogs (n = 2), all characterized as T. cruzi TcIII/V (18S rDNA) and TcIII/V/VI (gGAPDH); one positive
skin fragment for Leishmania sp. (C. thous), one positive skin culture (Chrysocyon brachyurus) and
one positive fresh blood examination from a dog. Infection by T. cruzi and Leishmania spp. was
serologically confirmed in 18% and 4% of the canids, respectively. Active transmission was attested by
seroconversion events and occurred despite the low rate of positive parasitological assays. Wild and
domestic canids infected by both parasites were detected sharing the same areas, pointing to a possible
spillover of parasites among them. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal da Paraíba. Centro de Ciências Aplicadas e Educação. Campus IV, Litoral Norte, Rio Tinto, PB, Brasil / Programa de Conservação Mamíferos do Cerrado. Catalão, GO, Brasil. | pt_BR |
| Affilliation | Programa de Conservação Mamíferos do Cerrado. Catalão, GO, Brasil / Fundação Parque Zoológico de São Paulo. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Programa de Conservação Mamíferos do Cerrado. Catalão, GO, Brasil / Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Programa de Conservação Mamíferos do Cerrado. Catalão, GO, Brasil / Universidade Federal de Catalão. Departamento de Ciências Biológicas. Catalão, GO, Brasil. | pt_BR |
| Affilliation | Programa de Conservação Mamíferos do Cerrado. Catalão, GO, Brasil / Universidade Federal de Catalão. Departamento de Ciências Biológicas. Catalão, GO, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Groecosystems | pt_BR |
| Subject | Brazilian Cerrado | pt_BR |
| Subject | Cerdocyon thous | pt_BR |
| Subject | Lycalopex vetulus | pt_BR |
| Subject | Chrysocyon brachyurus | pt_BR |
| Subject | Canis lupus familiaris; | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Leishmania spp | pt_BR |
| Subject | Neotropical mammals | pt_BR |
