| Author | Caetano, Oswaldo Aparecido | |
| Author | Dutok, Carlos M. S. | |
| Author | Siqueira, Cristiane de Souza | |
| Author | Norberg, Paulo Roberto Blanco Moreira | |
| Author | Norberg, Antonio Neres | |
| Author | Queiroz, Margareth Maria de C. | |
| Access date | 2021-01-30T19:04:42Z | |
| Available date | 2021-01-30T19:04:42Z | |
| Document date | 2020 | |
| Citation | CAETANO, Oswaldo Aparecido et al. Human leptospirosis in teh city of Vassouras, province of Rio de Janeiro. World Journal of Pharmacy and Pharmaceutical Sciences, v. 9, n. 7, p. 2171-2182, 2020. | pt_BR |
| ISSN | 2278 – 4357 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/45887 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Leptospira | pt_BR |
| Subject in Portuguese | Leptospirose | pt_BR |
| Subject in Portuguese | Sorogrupo | pt_BR |
| Title | Human Leptospirosis in the city of Vassouras, province of Rio de Janeiro, Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.tmaid.2017.07.010 | |
| Abstract | Leptospirosis is a widespread systemic acute infectious disease caused by serovars of the bacteria of the Genus Leptospira. The etiologic agent of the disease is mainly transmitted through infected animals’ urine, being domestic and wild animals the reservoir. Humans are accidental hosts within the transmission chain. Some serovars of Leptospira can be harmful to humans. The objective of this research was to estimate the incidence of infection by serovars of the Genus Leptospira through serological analysis of individuals living in the city of Vassouras, Province of Rio de Janeiro, Brazil. Venous blood
samples were collected from 51 volunteers inhabitants of Vassouras, and the sera were submitted to microagglutination tests for detection of specific antibodies to Leptospira serovars. Among the 51 volunteer individuals participating in the research, 13 (25.5%) were positive to Leptospira serovars. In most samples, tests reacted to multiple serovars antibodies. The registered serovars distributed by samples were: Hebdomadis (92%), Patoc (69,23%), Pomona (53,85%), Castellonis (46.15%) Copenhageni (38, 46%), Grippotyphosa (38,46%) and Javanica (38,46%) Panama (30, 77%) Australis (23,08%), Canicola (23,08%), Tarassovi (23,08%), Autumnalis (15,38%), Bataviae (15,38%), Sejroe (15,38%) and Pyrogenes (7,69%). Although pathogenic serovars were not found among Vassouras inhabitants sera, the high prevalence of less pathogenic serovars (25,5%) points to high exposure to rodents’ urine and a consequent high risk for acquiring the severe form of leptospirosis if pathogenic serovars arise with migrant infect rodents to the city. | pt_BR |
| Affilliation | Universidade de Vassouras. Mestrado Profissional em Ciências Ambientais.Vassouras, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Amapá. Departamento de Ciências Fisiológicas. Curso de Enfermagem Campus Binacional Oiapoque / Centro Universitário Leonardo da Vinci / Centro Universitário Unifaveni. Uniasselvi. | pt_BR |
| Affilliation | Universidade de Vassouras. Mestrado Profissional em Ciências Ambientais.Vassouras, RJ, Brasil. | pt_BR |
| Affilliation | Escola Metropolitana São Carlos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Escola Metropolitana São Carlos. Rio de Janeiro, RJ, Brasil / Centro Universitário Uniaabeu. Belfor Roxo, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Entomologia Forense. Rio de Janeiro, RJ, Brasil / Instituto de Biologia do Exercito. Rio de Janeiro, RJ, Brasil / Universidade de Vassouras. Mestrado Profissional em Ciências Ambientais. Vassouras, RJ, Brasil / Bolsa de Estudos Produtividade da Pesquisa CNPQ. Estudos de Nível 1C e Bolsa de Cientistas da FAPERJ. | pt_BR |
| Subject | Leptospira | pt_BR |
| Subject | Leptospirosis | pt_BR |
| Subject | Serovars | pt_BR |
| Subject | Vassouras | pt_BR |
| DeCS | Sorogrupo | pt_BR |
