| Author | Menezes-Neto, Armando | |
| Author | Castilho, Marcia da Costa | |
| Author | Calvet, Guilherme Amaral | |
| Author | Kara, Edna Oliveira | |
| Author | Bôtto-Menezes, Camila Helena Aguiar | |
| Author | Lacerda, Marcus Vinícius Guimarães | |
| Author | Pereira, Gerson Fernando Mendes | |
| Author | Giozza, Silvana Pereira | |
| Author | Bermudez, Ximena Pamela Diaz | |
| Author | Lima, Noemia Santana | |
| Author | Modjarrad, Kayvon | |
| Author | Broutet, Nathalie | |
| Author | Filippis, Ana Maria Bispo de | |
| Author | Franca, Rafael Freitas Oliveira | |
| Author | Study Team ZIKABRA | |
| Access date | 2021-02-09T21:01:41Z | |
| Available date | 2021-02-09T21:01:41Z | |
| Document date | 2021 | |
| Citation | MENEZES-NETO, Armando et al. Zika virus RNA excretion in sweat with concomitant detection in other body fluid specimens. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 115, e200339, p. 1-5, 2020. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/46023 | |
| Description | ZIKABRA Study Team members (in alphabetical order): Ana Izabel Costa de Menezes, Ana Maria Bispo de Filippis, André Luiz de Abreu, Anna Thorson, Armando Menezes Neto, Camila Helena Aguiar Bôtto-Menezes, Carlos Alexandre Antunes Brito, Casey Storme, Cristina Pimenta, Edna Oliveira Kara, Gerson Fernando Mendes Pereira, Guilherme Amaral Calvet, Kayvon Modjarrad, Lydie Trautman, Maeve Brito de Mello, Marcia da Costa Castilho, Marcus Vinicius Guimarães Lacerda, Morganna Costa Lima, Nathalie Jeanne Nicole Broutet, Ndema Habib, Noemia Lima, Patrícia Brasil, Rafael Freitas Oliveira Franca, Sihem Landoulsi, Silvana Pereira Giozza, Ute Ströher, Ximena Pamela Diaz Bermudez. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Scielo | pt_BR |
| Rights | open access | |
| Title | Zika virus RNA excretion in sweat with concomitant detection in other body fluid specimens | pt_BR |
| Type | Article | |
| DOI | 10.1590/0074-02760200339 | |
| Abstract | We evaluated sweat, blood and urine specimens obtained from an ongoing cohort study in Brazil. Samples were collected at pre-established intervals after the initial rash presentation and tested for Zika virus (ZIKV) RNA presence by real-time reverse transcriptase polymerase chain reaction (rRT-PCR). From 254 participants with confirmed infection, ZIKV RNA was detected in the sweat of 46 individuals (18.1%). Sweat presented a median cycle threshold (Ct) of 34.74 [interquartile range (IQR) 33.44-36.04], comparable to plasma (Ct 35.96 - IQR 33.29-36.69) and higher than urine (Ct 30.78 - IQR 28.72-33.22). Concomitant detection with other specimens was observed in 33 (72%) of 46 participants who had a positive result in sweat. These findings represent an unusual and not yet investigated virus shedding through eccrine glands. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação de Medicina Tropical Doutor Heitor Vieira Dourado. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | World Health Organization. Geneva, Switzerland. | pt_BR |
| Affilliation | Universidade do Estado do Amazonas. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil. | pt_BR |
| Affilliation | Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis. Brasília, DF, Brasil. | pt_BR |
| Affilliation | Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis. Brasília, DF, Brasil. | pt_BR |
| Affilliation | Organização Pan Americana de Saúde/Organização Mundial da Saúde. Universidade de Brasília. Departamento de Saúde Pública. Brasília, DF, Brasil. | pt_BR |
| Affilliation | Henry M Jackson Foundation for the Advancement of Military Medicine. Bethesda, MD, USA / Walter Reed Army Institute of Research. Silver Spring, MD, USA. | pt_BR |
| Affilliation | Walter Reed Army Institute of Research. Silver Spring, MD, USA. | pt_BR |
| Affilliation | World Health Organization. Geneva, Switzerland. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Subject | Zika virus | pt_BR |
| Subject | Diagnosis | pt_BR |
| Subject | Persistence | pt_BR |
