| Author | Lyra, Marcelo Rosandiski | |
| Author | Sokoloski, Vanessa | |
| Author | Macedo, Priscila Marques de | |
| Author | Azevedo, Anna Carolina Procópio de | |
| Access date | 2021-04-22T14:44:29Z | |
| Available date | 2021-04-22T14:44:29Z | |
| Document date | 2021 | |
| Citation | LYRA, Marcelo Rosandiski et al. Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide. Anais brasileiros de dermatologia, v. 96, n. 2, p. 231-233, 2021 | |
| URI | https://www.arca.fiocruz.br/handle/icict/46838 | |
| Language | eng | en_US |
| Publisher | Elsevier | |
| Rights | restricted access | |
| Subject in Portuguese | Cryosurgery | pt_BR |
| Subject in Portuguese | Itraconazole | pt_BR |
| Subject in Portuguese | Potassium iodide | pt_BR |
| Subject in Portuguese | Sporothrix | pt_BR |
| Subject in Portuguese | Sporotrichosis | pt_BR |
| Title | Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide | en_US |
| Type | Preprint | |
| Abstract | Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix brasiliensis was the identified species, presenting a susceptibility profile to itraconazole and terbinafine. This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Hospital Central Aristarcho Pessoa. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
