| Author | Ramos, Aline de Souza | |
| Author | Fiaux, Sorele Batista | |
| Author | Leite, Selma Gomes Ferreira | |
| Access date | 2021-05-31T19:44:22Z | |
| Available date | 2021-05-31T19:44:22Z | |
| Document date | 2008 | |
| Citation | RAMOS, Aline de Souza; FIAUX, Sorele Batista; LEITE, Selma Gomes Ferreira. Production of 6-pentyl-alpha-pyrone by Trichoderma harzianum in solid-state fermentation. Brazilian Journal of Microbiology, v. 39, p. 712-717, 2008. | pt_BR |
| ISSN | 1517-8382 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/47468 | |
| Language | por | pt_BR |
| Rights | open access | pt_BR |
| Title | Production of 6-pentyl-alpha-pyrone by Trichoderma harzianum in solid-state fermentation | pt_BR |
| Type | Article | pt_BR |
| Abstract | Many Trichoderma species are able to produce 6-pentyl-α-pyrone (6-PP), a lactone with coconut-like aroma. In the present work, several culture parameters were studied to enhance the production of 6-PP by Trichoderma harzianum 4040 in solid-state fermentation. Green coir powder added to a nutrient solution was used as support material for fermentation. A Plackett-Burman screening technique was applied, followed by a fractionary factorial design. The best culture conditions within the experimental domain studied were (100 g support)-1: sucrose, 3 g; NaNO3, 0.24 g; (NH4)2SO4, 0.18 g; KH2PO4, 0.1 g; inoculum concentration, 2.2 x 106 spores; moisture level, 55%. The temperature established was 28ºC. The fermentation under the selected conditions led to a 6-PP production six times higher (5.0 mg/g dry matter) than the initial one (0.8 mg/g dry matter) after seven days of cultivation. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Escola de Química. Departamento de Engenharia Bioquímica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Faculdade de Farmácia. Niterói, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Escola de Química. Departamento de Engenharia Bioquímica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | 6-pentyl-α-pyrone | pt_BR |
| Subject | Trichoderma Harzianum | pt_BR |
| Subject | Solid-State Fermentation | pt_BR |
| Subject | Experimental Design | pt_BR |
