| Author | Schechtman, Helio | |
| Author | Valle, Denise | |
| Author | Souza, Max O. | |
| Access date | 2021-06-17T14:19:38Z | |
| Available date | 2021-06-17T14:19:38Z | |
| Document date | 2020 | |
| Citation | SCHECHTMAN, Helio; VALLE, Denise; SOUZA, Max. O. From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide. Plos Negl Trop Dis., v. 14, n. 11, e0008862, 17 p, Nov. 2020. | pt_BR |
| ISSN | 1935-2727 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/47744 | |
| Language | eng | pt_BR |
| Publisher | Public Library of Science | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Modelo matemático | pt_BR |
| Subject in Portuguese | Uso indiscriminado | pt_BR |
| Subject in Portuguese | Inseticidas | pt_BR |
| Title | From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide | pt_BR |
| Type | Article | |
| DOI | 10.1371/journal.pntd.0008862 | |
| Abstract | The development of insecticide resistance is becoming a threat to many arboviruses control
programs worldwide. While this has been attributed to the indiscriminate use of insecticide,
a more theoretical study is apparently not available. Using in-silico experiments, we investi gated the effects of two different policies: one used by the Brazilian Ministry of Health (which
follows the World Health Organization protocol) and a more permissive one, akin to those
employed by various gated communities and private companies. The results show that the
public policy does not lead to resistance fixation. On the other hand, permissive application
of adulticide, such as intensive domestic use mainly during epidemic periods, might lead to
the fixation of a resistant population, even when resistance is associated with moderate fit ness costs. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Flavivírus. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM)/CNPq. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Instituto de Matemática e Estatística. Niterói, RJ, Brasil. | pt_BR |
| Subject | Mathematical model | pt_BR |
| Subject | Indiscriminate use | pt_BR |
| Subject | Insecticide | pt_BR |
| e-ISSN | 1935-2735 | |
