| Author | Nicacio, Jandir Mendonça | pt_BR |
| Author | Cunha, Antonio Ricardo Khouri | pt_BR |
| Author | Silva, Antônio Marconi Leandro da | pt_BR |
| Author | Barral-Netto, Manoel | pt_BR |
| Author | Lima, João Augusto Costa | pt_BR |
| Author | Ladeia, Ana Marice Teixeira | pt_BR |
| Author | Carmo, Rodrigo Feliciano do | pt_BR |
| Author | Armstrong, Anderson da Costa | pt_BR |
| Access date | 2021-07-14T18:15:22Z | |
| Available date | 2021-07-14T18:15:22Z | |
| Document date | 2021 | |
| Citation | NICACIO, Jandir Mendonça et al. Anti-chikungunya virus seroprevalence in Indigenous groups in the São Francisco Valley,
Brazil. PLoS Neglected Tropical Diseases, v. 15, n. 6, p. 1-13, Jun. 2021. | pt_BR |
| ISSN | 1935-2727 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/48239 | |
| Sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico-CNPq"- Ministry of Science, Technology, Innovations and Communications of Brazil (link: < https://www.gov.br/cnpq/pt-br>) provided logistical support and funding for the laboratory tests performed in the study. Funding was allocated to ACA. We
acknowledge Fundac¸a˜o Maria Emilia for the grant regarding the publication fee and further research on this topic. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | pt_BR |
| Sponsorship | Fundação Maria Emília. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Public Library of Science | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Vírus Chikungunya | pt_BR |
| Subject in Portuguese | Febre de Chikungunya | pt_BR |
| Subject in Portuguese | Grupos populacionais | pt_BR |
| Subject in Portuguese | Estudos soroepidemiológicos | pt_BR |
| Subject in Portuguese | Saúde pública | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Anti-chikungunya virus seroprevalence in indigenous groups in the São Francisco Valley, Brazil | en |
| Type | Article | pt_BR |
| DOI | 10.1371/journal.pntd.0009468 | pt_BR |
| Abstract | Background: Chikungunya fever (CHIKF) is a serious public health problem with a high rate of infection and chronic disabling manifestations that has affected more than 2 million people worldwide since 2005. In spite of this, epidemiological data on vulnerable groups such as Indigenous people are scarce, making it difficult to implement public policies in order to prevent this disease and assist these populations. Objective: To describe the serological and epidemiological profile of chikungunya virus (CHIKV) in two Indigenous populations in Northeast Brazil, as well as in an urbanized control community, and to explore associations between CHIKV and anthropometric variables in these populations. Methodology/Principal findings: This is a cross-sectional ancillary study of the Project of Atherosclerosis among Indigenous Populations (PAI) that included people 30 to 70 years old, recruited from two Indigenous tribes (the less urbanized Fulni-ô and the more urbanized Truká people) and an urbanized non-Indigenous control group from the same area. Subjects underwent clinical evaluation and were tested for anti-CHIKV IgG by enzyme-linked immunosorbent assay. Serological profile was described according to ethnicity, sex, and age. The study population included 433 individuals distributed as follows: 109 (25·2%) Truká, 272 (62·8%) Fulni-ô, and 52 (12%) from the non-Indigenous urbanized control group. Overall prevalence of CHIKV IgG in the study sample was 49.9% (216; 95% CI: 45·1–54·7). When the sample was stratified, positive CHIKV IgG was distributed as follows: no individuals in the Truká group, 78·3% (213/272; 95% CI: 72·9–83·1) in the Fulni-ô group, and 5.8% (3/52; 95% CI: 1.21–16) in the control group. Conclusions/Significance: Positive tests for CHIKV showed a very high prevalence in a traditional Indigenous population, in contrast to the absence of anti-CHIKV serology in the Truká people, who are more urbanized with respect to physical landscape, socio-cultural, and historical aspects, as well as a low prevalence in the non-Indigenous control group, although all groups are located in the same area. | en |
| Affilliation | Universidade Federal do Vale do São Francisco. Curso de Medicina. Petrolina, PE, Brasil / Universidade Federal do Vale do São Francisco. Centro de Estudos em Saúde. Programa de Pós-Graduação Ciências da Saúde e Biológicas. Petrolina, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Rega Institute for Medical Research. Leuven, Belgium. | pt_BR |
| Affilliation | Universidade Federal do Vale do São Francisco. Curso de Medicina. Petrolina, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Johns Hopkins University. Heart and Vascular Institute. Cardiology Team. Baltimore, MD, USA. | pt_BR |
| Affilliation | Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Vale do São Francisco. Petrolina, PE, Brasil / Universidade Federal do Vale do São Francisco. Colegiado de Ciências Farmacêuticas. Petrolina, PE, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Vale do São Francisco. Curso de Medicina. Petrolina, PE, Brasil / Universidade Federal do Vale do São Francisco. Centro de Estudos em Saúde. Programa de Pós-Graduação Ciências da Saúde e Biológicas. Petrolina, PE, Brasil. | pt_BR |
| Subject | Chikungunya virus | en |
| Subject | Chikungunya fever | en |
| Subject | Population groups | en |
| Subject | Seroepidemiologic studies | en |
| Subject | Public health | en |
| Subject | Brazil | en |
| e-ISSN | 1935-2735 | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
