| Author | Teixeira, Maria de Lourdes Benamor | |
| Author | Ferreira Júnior, Orlando da Costa | |
| Author | João, Esaú | |
| Author | Fuller, Trevon | |
| Author | Esteves, Juliana Silva | |
| Author | Mendes-Silva, Wallace | |
| Author | Mocarzel, Carolina Carvalho | |
| Author | Maia, Richard Araújo | |
| Author | Boullosa, Lídia Theodoro | |
| Author | Gonçalves, Cássia Cristina Alves | |
| Author | Frankel, Patrícia Pontes | |
| Author | Gouvêa, Maria Isabel Fragoso da Silveira | |
| Access date | 2021-09-01T22:48:08Z | |
| Available date | 2021-09-01T22:48:08Z | |
| Document date | 2021 | |
| Citation | TEIXEIRA, Maria de Lourdes Benamor et al. Maternal and Neonatal Outcomes of SARS-CoV-2 Infection in a Cohort of Pregnant Women with Comorbid Disorders. Viruses, v. 13, n. 7, p. 1-10, 2021. | pt_BR |
| ISSN | 1999-4915 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/48907 | |
| Language | eng | pt_BR |
| Publisher | MDPI | pt_BR |
| Rights | open access | pt_BR |
| Title | Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.3390/v13071277 | |
| Abstract | There are some reports and case series addressing Coronavirus Disease 2019 (COVID-19) infections during pregnancy in upper income countries, but there are few data on pregnant women with comorbid conditions in low and middle income Countries. This study evaluated the proportion and the maternal and neonatal outcomes associated with SARS-CoV-2 infection among pregnant women with comorbidities. Participants were recruited consecutively in order of admission to a maternity for pregnant women with comorbidities. Sociodemographic, clinical, and laboratory data were prospectively collected during hospitalization. Pregnant women were screened at entry: nasopharyngeal swabs were tested by RT-PCR; serum samples were tested for IgG antibodies against spike protein by ELISA. From April to June 2020, 115 eligible women were included in the study. The proportion of SARS-CoV-2 infection was 28.7%. The rate of obesity was 60.9%, vascular hypertension 40.0%, and HIV 21.7%. The most common clinical presentations were ageusia (21.2%), anosmia (18.2%), and fever (18.2%). Prematurity was higher among mothers who had a SARS-CoV-2 infection based on RT-PCR. There were two cases of fetal demise. We found a high proportion of COVID-19 among pregnant women with comorbidities. This underscores the importance of antenatal care during the pandemic to implement universal SARS-CoV-2 screening, precautionary measures, and the rollout of vaccination programs for pregnant women. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Maternidade Escola. Programa de Saúde Perinatal. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | HIV | pt_BR |
| Subject | SARS-CoV-2 | pt_BR |
| Subject | Obesity | pt_BR |
| Subject | Obstetrics | pt_BR |
| Subject | Pregnancy | pt_BR |
