Author | Sales Junior, Sidney Fernandes | |
Author | Amaral, Isabeke Campos Costa | |
Author | Mannarino, Camille Ferreira | |
Author | Hauser-Davis, Rachel Ann | |
Author | Correia, Fábio Veríssimo | |
Author | Saggioro, Enrico Mendes | |
Access date | 2021-09-03T14:20:29Z | |
Available date | 2021-09-03T14:20:29Z | |
Document date | 2021 | |
Citation | SALES JUNIOR, Sidney Fernandes et al. Long-term landfill leachate exposure modulates antioxidant responses and causes cyto-genotoxic effects in Eisenia andrei earthworms. Environmental Pollution, v. 287, 117351, 11 p, May 2021. | pt_BR |
ISSN | 0269-7491 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/48956 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Lixiviação de aterro | pt_BR |
Subject in Portuguese | Peroxidação lipídica | pt_BR |
Subject in Portuguese | Sistema antioxidante | pt_BR |
Subject in Portuguese | Coelomócitos | pt_BR |
Title | Long-term landfill leachate exposure modulates antioxidant responses and causes cyto-genotoxic effects in Eisenia andrei earthworms | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.envpol.2021.117351 | |
Abstract | It is estimated that approximately 0.4% of the total leachate produced in a landfill is destined for treatment
plants, while the rest can reach the soil and groundwater. In this context, this study aimed to perform leachate
toxicity evaluations through immune system cytotoxic assessments, genotoxic (comet assay) appraisals and
antioxidant system (superoxide dismutase - SOD; catalase - CAT, glutathione-S-transferase - GST; reduced
glutathione - GSH and metallothionein - MT) evaluations in Eisenia andrei earthworms exposed to a Brazilian
leachate for 77 days. The leachate sample contained high organic matter (COD - 10,630 mg L− 1
) and ammoniacal
nitrogen (2398 mg L− 1
), as well as several metals, including Ca, Cr, Fe, Mg, Ni and Zn. Leachate exposure
resulted in SOD activity alterations and increased CAT activity and MT levels. Decreased GST activity and GSH
levels were also observed. Antioxidant system alterations due to leachate exposure led to increased malondial dehyde levels as a result of lipid peroxidation after the 77 day-exposure. An inflammatory process was also
observed in exposed earthworms, evidenced by increased amoebocyte density, and DNA damage was also noted.
This study demonstrates for the first time that sublethal effect assessments in leachate-exposed earthworms
comprise an important tool for solid waste management. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Centro de Estudos em Saúde do Trabalhador e Ecologia Humana. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Centro de Estudos em Saúde do Trabalhador e Ecologia Humana. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Saneamento e Saúde Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Estado do Rio de Janeiro-UNIRIO. Departamento de Ciências Naturais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Centro de Estudos em Saúde do Trabalhador e Ecologia Humana. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Saneamento e Saúde Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Landfill leachate | pt_BR |
Subject | Lipid peroxidation | pt_BR |
Subject | Antioxidant system | pt_BR |
Subject | Coelomocytes | pt_BR |
Subject | Comet assay | pt_BR |
Embargo date | 2023 | |
xmlui.metadata.dc.subject.ods | 12 Consumo e produção responsáveis | |