| Author | Silva, Mayara Torquato Lima da | |
| Author | Deodato, Raissa Martins | |
| Author | Villar, Lívia Melo | |
| Access date | 2021-09-12T19:15:42Z | |
| Available date | 2021-09-12T19:15:42Z | |
| Document date | 2021 | |
| Citation | SILVA, Mayara Torquato Lima da; DEODATO, Raissa Martins; VILLAR, Lívia Melo. Exploring the potential usefulness of IgY for antiviral therapy: A current review. International Journal of Biological Macromolecules, v. 189, p. 785-791, Aug. 2021. | pt_BR |
| ISSN | 0141-8130 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/49060 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Immunoglobulin Y | pt_BR |
| Subject in Portuguese | Imunoterapia | pt_BR |
| Subject in Portuguese | Anticorpo de gema de ovo | pt_BR |
| Title | Exploring the potential usefulness of IgY for antiviral therapy: A current review | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.ijbiomac.2021.08.078 | |
| Abstract | Immunoglobulin yolk (IgY) is therapeutic antibodies presented in yolk eggs of birds, reptiles, and amphibians.
These proteins produced by the immune system of the animal, are capable of neutralizing antigenic molecules,
including viral antigens, fulfilling a role in the body defense. The specificity of these antibodies and the facility
for their production, make these molecules capable of being used as tools for diagnosis and immunotherapy.
Regarding this last aspect, it is common knowledge that the field of virology, is racing against time in the
development of new drugs and vaccines to try to contain pandemics and local epidemics and, in counterproposal,
avian antibodies are neutralizing molecules that can help in the control and spread of disease. These molecules
have been explored for years and currently chicken eggs are produced in large quantities from the animal's
immunization against a specific pathogen. Thus, on this subject, this review made a survey of these researches
and presents a summary of all the successful cases and perspectives in the use of IgYs as tools for viral
immunization. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Immunoglobulin Y | pt_BR |
| Subject | Immunoglobulin Y | pt_BR |
| Subject | Egg yolks antibody | pt_BR |
| Embargo date | 2023 | |
