| Author | Moraes, Marcia Terezinha Baroni de | |
| Author | Leitão, Gabriel Azevedo Alves | |
| Author | Olivares, Alberto Ignácio Olivares | |
| Author | Xavier, Maria da Penha Trindade Pinheiro | |
| Author | Bispo, Romanul de Souza | |
| Author | Sharma, Sumit | |
| Author | Leite, José Paulo Gagliardi | |
| Author | Svensson, Lennart | |
| Author | Nordgren, Johan | |
| Access date | 2021-10-06T10:08:20Z | |
| Available date | 2021-10-06T10:08:20Z | |
| Document date | 2021 | |
| Citation | MORAES, Marcia Terezinha Baroni de et al. Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region. Pathogens, v. 10, n. 965, 10 p, July 2021. | pt_BR |
| ISSN | 2076-0817 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/49286 | |
| Language | eng | pt_BR |
| Publisher | MDPI | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Sapovírus | pt_BR |
| Subject in Portuguese | Antígeno do grupo histo-sangue | pt_BR |
| Subject in Portuguese | Região Amazônica | pt_BR |
| Title | Molecular Epidemiology of Sapovirus in Children Living in the Northwest Amazon Region | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.3390/pathogens10080965 | |
| Abstract | Sapovirus is an important etiological agent of acute gastroenteritis (AGE), mainly in
children under 5 years old living in lower-income communities. Eighteen identified sapovirus
genotypes have been observed to infect humans. The aim of this study was to identify sapovirus
genotypes circulating in the Amazon region. Twenty-eight samples were successfully genotyped
using partial sequencing of the capsid gene. The genotypes identified were GI.1 (n = 3), GI.2 (n = 7),
GII.1 (n = 1), GII.2 (n = 1), GII.3 (n = 5), GII.5 (n = 1), and GIV.1 (n = 10). The GIV genotype was the
most detected genotype (35.7%, 10/28). The phylogenetic analysis identified sapovirus genotypes
that had no similarity with other strains reported from Brazil, indicating that these genotypes may
have entered the Amazon region via intense tourism in the Amazon rainforest. No association
between histo-blood group antigen expression and sapovirus infection was observed. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Insituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Insituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Secretaria Estadual de Saúde de Roraima. Boa Vista, RR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Insituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Roraima. Centro de Pesquisa Observatório da Saúde de Roraima. Boa Vista, RR, Brasil. | pt_BR |
| Affilliation | Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology. Linköping University, 581 85 Linköping, Sweden. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Insituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology. Linköping University, 581 85 Linköping, Sweden / Department of Medicine, Division of Infectious Diseases, Karolinska Institute, 171 76 Stockholm, Sweden. | pt_BR |
| Affilliation | Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology. Linköping University, 581 85 Linköping, Sweden. | pt_BR |
| Subject | Sapovirus | pt_BR |
| Subject | Histo-blood group antigen | pt_BR |
| Subject | Amazon region | pt_BR |
