| Author | Carmona-Peña, S. P. | |
| Author | Contreras-Garduño, J. | |
| Author | Castro, D. P. | |
| Author | Manjarrez, J. | |
| Author | Vázquez-Chagoyán, C. | |
| Access date | 2021-11-10T15:08:32Z | |
| Available date | 2021-11-10T15:08:32Z | |
| Document date | 2021 | |
| Citation | CARMONA-PEÑA, S. P. et al. The innate immune response of triatomines against Trypanosoma cruzi and Trypanosoma rangeli with an unresolved question: do triatomines have immune memory?. Acta Tropica, v. 224, p. 1-7, 2021. | pt_BR |
| ISSN | 0001-706X | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/49767 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Interação parasita-hospedeiro | pt_BR |
| Subject in Portuguese | Eco-imunologia | pt_BR |
| Subject in Portuguese | Doença de Chagas | pt_BR |
| Subject in Portuguese | Priming imunológico | pt_BR |
| Subject in Portuguese | Imunidade inata | pt_BR |
| Subject in Portuguese | Vetores | pt_BR |
| Title | The innate immune response of triatomines against Trypanosoma cruzi and Trypanosoma rangeli with an unresolved question: do triatomines have immune memory? | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.actatropica.2021.106108 | pt_BR |
| Abstract | The present work aimed to review the immune response from different triatomines against Trypanosoma cruzi and Trypanosoma rangeli and propose the study of immune memory in such insects. Trypanosoma use triatomines as vectors to reach and infect mammals. A key question to be answered about vector-parasite interaction is why the immune defense and resistance of the insect against the parasites vary. Up to date data shows that the defense of triatomines against parasites includes cellular (phagocytosis, nodulation and encapsulation) and humoral (antimicrobial peptides, phenoloxidase and reactive oxygen and nitrogen species) responses. The immune response varies depending on the triatomine species, the trypanosome strain and species, and the insect intestinal microbiota. Despite significant advances to understand parasite-insect interaction, it is still unknown if triatomines have immune memory against parasites and if this memory may derive from tolerance to parasites attack. Therefore, a closer study of such interaction could contribute and establish new proposals to control the parasite at the vector level to reduce parasite transmission to mammals, including men. For instance, if immune memory exists in the triatomines, it would be interesting to induce weak infections in insects to find out if subsequent infections are less intense and if the insects succeed in eliminating the parasites. | en |
| Affilliation | Universidad Autónoma del Estado de México. Facultad de Medicina Veterinaria y Zootecnia. Programa de Maestría en Ciencias Agropecuarias y Recursos Naturales. Estado de México, México / Universidad Autónoma del Estado de México. Facultad de Medicina Veterinaria y Zootecnia. Centro de Investigación y Estudios Avanzados en Salud Animal. Estado de México, México. | pt_BR |
| Affilliation | Universidad Nacional Autónoma de México. Escuela Nacional de Estudios Superiores. Morelia, Michoacán, México. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidad Autónoma del Estado de México. Facultad de Ciencias. Instituto Literario. Toluca, Estado de México, México. | pt_BR |
| Affilliation | Universidad Autónoma del Estado de México. Facultad de Medicina Veterinaria y Zootecnia. Centro de Investigación y Estudios Avanzados en Salud Animal. Estado de México, México. | pt_BR |
| Subject | Host-parasite interaction | en |
| Subject | Eco-immunology | en |
| Subject | Chagas disease | en |
| Subject | Immune priming | en |
| Subject | Innate immunity | en |
| Subject | Vectors | en |
| Embargo date | 2023 | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
