| Author | Torres, Rosália Morais | |
| Author | Correia, Dalmo | |
| Author | Nunes, Maria do Carmo Pereira | |
| Author | Dutra, Walderez O. | |
| Author | Talvani, André | |
| Author | Sousa, Andréa Silvestre | |
| Author | Mendes, Fernanda de Souza Nogueira Sardinha | |
| Author | Scanavaccax, Maurício Ibrahim | |
| Author | Ibrahim, Maurício | |
| Author | Moreira, Maria da Consolação Vieira | |
| Author | Souza, Dilma do Socorro Moraes de | |
| Author | Oliveira Junior, Wilson de | |
| Author | Martins, Silvia Marinho | |
| Author | Dias, João Carlos Pinto | |
| Access date | 2021-12-21T23:33:00Z | |
| Available date | 2021-12-21T23:33:00Z | |
| Document date | 2021 | |
| Citation | TORRES, Rosália Moraes et al. Prognosis of chronic Chagas heart disease and other pending clinical challenges. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 116, p. 1-17, 2021. | pt_BR |
| ISSN | 0074-0276 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/50513 | |
| Language | eng | pt_BR |
| Publisher | Instituto Oswaldo Cruz | pt_BR |
| Rights | open access | pt_BR |
| Title | Prognosis of chronic Chagas heart disease and other pending clinical challenges | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1590/0074-02760210172 | |
| Abstract | In this chapter, the main prognostic markers of Chagas heart disease are addressed, with an emphasis on the most recent
findings and questions, establishing the basis for a broad discussion of recommendations and new approaches to managing Chagas
cardiopathy. The main biological and genetic markers and the contribution of the electrocardiogram, echocardiogram and cardiac
magnetic resonance are presented. We also discuss the most recent therapeutic proposals for heart failure, thromboembolism and
arrhythmias, as well as current experience in heart transplantation in patients suffering from severe Chagas cardiomyopathy. The
clinical and epidemiological challenges introduced by acute Chagas disease due to oral contamination are discussed. In addition,
we highlight the importance of ageing and comorbidities in influencing the outcome of chronic Chagas heart disease. Finally,
we discuss the importance of public policies, the vital role of funding agencies, universities, the scientific community and health
professionals, and the application of new technologies in finding solutions for better management of Chagas heart disease. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Triângulo Mineiro. Uberaba, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Ouro Preto. Ouro Preto, MG, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto do Coração. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto do Coração. São Paulo, SP, Brasil. | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Pará. Belém, PA, Brasil. | pt_BR |
| Affilliation | Universidade de Pernambuco. Recife, PE, Brasil. | pt_BR |
| Affilliation | Universidade de Pernambuco. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Belo Horizonte, MG, Brasil. | pt_BR |
| Subject | Chagas disease | pt_BR |
| Subject | Chagas cardiomyopathy | pt_BR |
| Subject | Prognosis | pt_BR |
| Subject | Evolution markers | pt_BR |
| Subject | Public health | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
