Mostrar el registro sencillo del ítem
| Autor | Ruy, Patrícia de Cássia | |
| Autor | Torrieri, Raul | |
| Autor | Toledo, Juliano Simões | |
| Autor | Alves, Viviane de Souza | |
| Autor | Cruz, Angela Kaysel | |
| Autor | Ruiz, Jeronimo Conceição | |
| Fecha de acceso | 2022-01-28T16:03:56Z | |
| Fecha de disponibilización | 2022-01-28T16:03:56Z | |
| Fecha de publicación | 2014 | |
| Referencia | RUY, Patrícia de Cássia et al. Intrinsically disordered proteins (IDPs) in trypanosomatids. BMC Genomics, v. 15, 1100, 2014. https://doi.org/10.1186/1471-2164-15-1100 | pt_BR |
| ISSN | 1471-2164 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/50937 | |
| Promoción | COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR | pt_BR |
| Idioma | eng | pt_BR |
| Editor | BioMed Central | pt_BR |
| Derechos de autor | open access | pt_BR |
| Título | Intrinsically disordered proteins (IDPs) in trypanosomatids | pt_BR |
| Tipo del documento | Article | pt_BR |
| DOI | 10.1186/1471-2164-15-1100 | |
| Resumen en Inglés | Proteins are composed of one or more amino acid chains and exhibit several structure levels. IDPs (intrinsically disordered proteins) represent a class of proteins that do not fold into any particular conformation and exist as dynamic ensembles in their native state. Due to their intrinsic adaptability, IDPs participate in many regulatory biological processes, including parasite immune escape. Using the information from trypanosomatids proteomes, we developed a pipeline for the identification, characterization and analysis of IDPs. The pipeline employs six disorder prediction methodologies and integrates structural and functional annotation information, subcellular location prediction and physicochemical properties. At the core of the IDP pipeline, there is a relational database that describes the protein disorder knowledge in a logically consistent manner. | pt_BR |
| Afiliación | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Informática de Biossistemas. Belo Horizonte, MG, Brasil. | pt_BR |
| Afiliación | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Informática de Biossistemas. Belo Horizonte, MG, Brasil. | pt_BR |
| Afiliación | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Ribeirão Preto, SP, Brasil. | pt_BR |
| Afiliación | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil | pt_BR |
| Afiliación | Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Ribeirão Preto, SP, Brasil. | pt_BR |
| Afiliación | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Informática de Biossistemas. Belo Horizonte, MG, Brasil. | pt_BR |
Ficheros en el ítem
