Author | Gomes, Carolina Nogueira | |
Author | Barker, Dillon Oliver Reese | |
Author | Duque, Sheila da Silva | |
Author | Che, Emily Victoria | |
Author | Jayamanna, Vasena | |
Author | Taboada, Eduardo Napoleon | |
Author | Falcão, Juliana Pfrimer | |
Access date | 2022-01-31T18:03:48Z | |
Available date | 2022-01-31T18:03:48Z | |
Document date | 2021 | |
Citation | GOMES, Carolina Nogueira et al. Campylobacter coli isolated in Brazil typed by core genome Multilocus Sequence Typing shows high genomic diversity in a global context. Infection, Genetics and Evolution, v. 95, 105018, p. 1 - 8, 2021. | pt_BR |
ISSN | 1567-1348 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/50962 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Campylobacter coli | pt_BR |
Subject in Portuguese | Contexto global | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Subject in Portuguese | Digitação de Sequência Multilocus | pt_BR |
Subject in Portuguese | Tipagem de sequência multilocus do genoma central | pt_BR |
Title | Campylobacter coli isolated in Brazil typed by core genome Multilocus Sequence Typing shows high genomic diversity in a global context | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.meegid.2021.105018 | |
Abstract | Campylobacter has been one of the most common causative agent of bacterial food-borne gastroenteritis in
humans worldwide. However, in Brazil the campylobacteriosis has been a neglected disease and there is
insufficient data to estimate the incidence of this pathogen in the country.
Aims: The current study aimed to determine the phylogenetic relationships among Campylobacter coli strains
isolated in Brazil and to compare them with international Campylobacter isolates available in some public
databases.
Methods and results: A total of 63C. coli strains isolated in Brazil were studied. The MLST analysis showed 18
different STs including three STs not yet described in the PubMLST database. The cgMLST allocated the Brazilian
strains studied into five main clusters and each cluster comprised groups of strains with nearly identical cgMLST
profiles and with significant genetic distance observed among the distinct clusters. The comparison of the Brazilian
strains with 3401 isolates from different countries showed a wide distribution of these strains isolated in
this country.
Conclusions: The results showed a high similarity among some strains studied and a wide distribution of the
Brazilian strains when compared to isolates from different countries, which is an interesting data set since it
showed a high genetic diversity of these strains from Brazil in a global context. This study contributed for a better
genomic characterization of C. coli strains isolated in Brazil and provided important information about the diversity
of this clinically-relevant pathogen. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil. | pt_BR |
Affilliation | National Microbiology Laboratory, Public Health Agency of Canada. Winnipeg, Manitoba, Canada. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | National Microbiology Laboratory, Public Health Agency of Canada. Winnipeg, Manitoba, Canada. | pt_BR |
Affilliation | National Microbiology Laboratory, Public Health Agency of Canada. Winnipeg, Manitoba, Canada. | pt_BR |
Affilliation | National Microbiology Laboratory, Public Health Agency of Canada. Winnipeg, Manitoba, Canada. | pt_BR |
Affilliation | Universidade de São Paulo. Faculdade de Ciˆencias Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil. | pt_BR |
Subject | Campylobacter coli | pt_BR |
Subject | MLST | pt_BR |
Subject | cgMLST | pt_BR |
Subject | Global context | pt_BR |
Subject | Brazil | pt_BR |
Embargo date | 2024 | |