| Author | Gomes Filho, Isaac Suzart | |
| Author | Trindade, Soraya Castro | |
| Author | Cruz, Simone Seixas da | |
| Author | Figueiredo, Ana Claudia Morais Godoy | |
| Author | Hintz, Alexandre Marcelo | |
| Author | Adan, Luis Fernando Fernandes | |
| Author | Cerqueira, Eneida de Moraes Marcílio | |
| Author | Soares, Johelle de Santana Passos | |
| Author | Vianna, Maria Isabel Pereira | |
| Author | Coelho, Julita Maria Freitas | |
| Author | Alves, Claúdia Maria Coêlho | |
| Author | Barreto, Maurício Lima | |
| Author | Seymour, Gregory John | |
| Author | Loomer, Peter Michael | |
| Author | Scannapieco, Frank Andrew | |
| Access date | 2022-02-15T12:05:03Z | |
| Available date | 2022-02-15T12:05:03Z | |
| Document date | 2021 | |
| Citation | Gomes Filho, Isaac Suzart et al. Mothers’ high glycemic levels and the association between periodontitis and low birth weight. Journal of Periodontology, p. 1-12, 2021. | pt_BR |
| ISSN | 1943-3670 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/51195 | |
| Sponsorship | Fundação de Amparo à Pesquisa do Estado da Bahia. (FAPESB). O Conselho Nacional Desenvolvimento Científico e Tecnológico (CNPq). Universidade Estadual de Feira de Santana. | pt_BR |
| Language | eng | pt_BR |
| Publisher | American Academy of Periodontology | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Epidemiologia | pt_BR |
| Subject in Portuguese | Hemoglobina A Glicada | pt_BR |
| Subject in Portuguese | Recém-Nascido de Baixo Peso | pt_BR |
| Subject in Portuguese | Periodontia | pt_BR |
| Subject in Portuguese | Periodontite | pt_BR |
| Subject in Portuguese | Gravidez | pt_BR |
| Title | Mothers’ high glycemic levels and the association between periodontitis and low birth weight | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1002/jper.21-0406 | |
| Abstract | Background: Maternal hyperglycemia, periodontitis, and adverse gestational outcomes are important health problems. The present study investigated the hypothesis that periodontitis and the glycemic level ofmothers may have opposing influences on birth weight (BW). This study evaluated the effect of high glycemic levels, albeit within the normal range, on the association between periodontitis and low birth weight (LBW). Methods: A total of 732 women took part in this case-control study; 172 were mothers of children with LBW<2,500 g, and 560 were mothers of children with BW ≥2,500 g. The BW of newborns was obtained from medical records, and
information on socioeconomic-demographic, lifestyle behavior were obtained through interviews. Glycated hemoglobin (HbA1c) levels were evaluated, and full-mouth periodontal examination was carried out within 7 days postpartum. Hierarchical and logistic regression analysis evaluated the effect of glycemic levels on the association between periodontitis and LBW by subgroups, estimating odds ratios (OR) with 95% confidence intervals (95% CI). Results: In the group with HbA1c levels <5.6%, a statistically significant relationship
existed between periodontitis and LBW. Using the Centre for Disease Control/American Academy of Periodontics criteria, the ORadjusted was 1.55; 95% CI: 1.04 to 2.31; using the Gomes-Filho et al. criteria the ORadjusted was 1.91; 95% CI, 1.06 to 3.45. In the group with higher HbA1c levels but still within the normal
range (≥5.6% and <6.5%), the findings showed no association between periodontitis and LBW. Conclusion: Higher maternal glycemic levels within the normal range, inferior to those indicative of gestational diabetes, diabetes mellitus, or hyperglycemia, and periodontitis have opposing effects on BW, altering the association magnitude. | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Saúde. Feira de Santana, BA, Brasil. | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Saúde. Feira de Santana, BA, Brasil. | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Saúde. Feira de Santana, BA, Brasil / Universidade Federal do Recôncavo da Bahia. Centro de Ciências da Saúde. Santo Antônio de Jesus, BA, Brasil. | pt_BR |
| Affilliation | Secretaria Estadual de Saúde do Distrito Federal. Vigilância Epidemiológica. Brasília, DF, Brasil. | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Saúde. Feira de Santana, BA, Brasil. | pt_BR |
| Affilliation | Universidade Federal da Bahia. Departamento de Pediatria. Salvador, BA, Brasil. | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Saúde. Feira de Santana, BA, Brasil. | pt_BR |
| Affilliation | Universidade Federal da Bahia. Departamento de Odontologia Preventiva. Salvador, Bahia, Brasil. | pt_BR |
| Affilliation | Universidade Federal da Bahia. Departamento de Odontologia Preventiva. Salvador, Bahia, Brasil. | pt_BR |
| Affilliation | Universidade Estadual de Feira de Santana. Departamento de Saúde. Feira de Santana, BA, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Maranhão. Programa de Pós-Graduação em Odontologia. São Luís, MA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos em Saúde. Salvador, BA, Brasil. | pt_BR |
| Affilliation | School of Dentistry. The University of Queensland. Brisbane, Queensland, Australia. | pt_BR |
| Affilliation | School of Dentistry. The University of Texas Health Science Center at San Antonio. San Antonio, TX, USA. | pt_BR |
| Affilliation | Department of Oral Biology. University at Buffalo. Buffalo, NY, USA. | pt_BR |
| Subject | Epidemiology | pt_BR |
| Subject | Glycated Hemoglobin A | pt_BR |
| Subject | Infant, Low Birth Weight | pt_BR |
| Subject | Periodontics | pt_BR |
| Subject | Periodontitis | pt_BR |
| Subject | Pregnancy | pt_BR |
