| Author | Tavares, Naiara Clemente | |
| Author | Mourão, Marina Moraes | |
| Access date | 2022-03-21T12:50:09Z | |
| Available date | 2022-03-21T12:50:09Z | |
| Document date | 2021 | |
| Citation | TAVARES, Naiara Clemente; MOURÃO, Marina Moraes. Parasitemia Evaluation in Mice Infected with Schistosoma mansoni. Bio Protoc., v. 11, n. 10, e4017, 2021. doi: 10.21769/BioProtoc.4017. | pt_BR |
| ISSN | 2331-8325 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/51763 | |
| Language | eng | pt_BR |
| Publisher | Bio-protocol LLC | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Parasitemia Evaluation in Mice Infected with Schistosoma mansoni. | pt_BR |
| Type | Article | |
| DOI | 10.21769/BioProtoc.4017 | |
| Abstract | Schistosomiasis is a neglected tropical disease. Its treatment relies on the use of a single drug, praziquantel. Due to treatment limitations, an alternative for schistosomiasis chemotherapy is required; thus, a better understanding of parasite biology and host-parasite interactions is valuable to aid the identification of new anti-Schistosoma drugs. The parasite has a complex life cycle, which results in challenges regarding the evaluation of Schistosoma mansoni development and mammalian infection establishment. Accordingly, this protocol describes methodologies to evaluate: (1) adult worm growth; (2) reproduction; and (3) granuloma formation; and consequently allows more comprehensive knowledge of S. mansoni development in a natural biological system. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Helmintologia e Malacologia Médica. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Helmintologia e Malacologia Médica. Belo Horizonte, MG, Brazil. | pt_BR |
| Subject | Confocal | pt_BR |
| Subject | Granuloma | pt_BR |
| Subject | In vivo | pt_BR |
| Subject | Oogram | pt_BR |
| Subject | Parasitemia | pt_BR |
| Subject | Schistosoma mansoni | pt_BR |
