| Author | Caragata, Eric P | |
| Author | Dutra, Heverton L C | |
| Author | Sucupira, Pedro Henrique Ferreira | |
| Author | Ferreira, Alvaro Gil Araujo | |
| Author | Moreira, Luciano Andrade | |
| Access date | 2022-06-29T14:33:10Z | |
| Available date | 2022-06-29T14:33:10Z | |
| Document date | 2021 | |
| Citation | CARAGATA, Eric P et al. Wolbachia as translational science: controlling mosquito-borne pathogens. Trends Parasitol., v. 37, n. 12, p. 1050-1067, 2021. doi: 10.1016/j.pt.2021.06.007 | pt_BR |
| ISSN | 1471-4922 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/53578 | |
| Language | eng | pt_BR |
| Publisher | Elsevier Science | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Wolbachia as translational science: controlling mosquito-borne pathogens | pt_BR |
| Type | Article | |
| DOI | 10.1016/j.pt.2021.06.007 | |
| Abstract | In this review we examine how exploiting the Wolbachia-mosquito relationship has become an increasingly popular strategy for controlling arbovirus transmission. Field deployments of Wolbachia-infected mosquitoes have led to significant decreases in dengue virus incidence via high levels of mosquito population suppression and replacement, emphasizing the success of Wolbachia approaches. Here, we examine how improved knowledge of Wolbachia-host interactions has provided key insight into the mechanisms of the essential phenotypes of pathogen blocking and cytoplasmic incompatibility. And we discuss recent studies demonstrating that extrinsic factors, such as ambient temperature, can modulate Wolbachia density and maternal transmission. Finally, we assess the prospects of using Wolbachia to control other vectors and agricultural pest species | pt_BR |
| Affilliation | Florida Medical Entomology Laboratory. Department of Entomology and Nematology. Institute of Food and Agricultural Sciences. University of Florida. Vero Beach, FL, USA. | pt_BR |
| Affilliation | Department of Biology. Pennsylvania State University. University Park, PA, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Mosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Mosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Mosquitos Vetores: Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil. | pt_BR |
| Subject | Wolbachia–host interactions | pt_BR |
| Subject | arbovirus; cytoplasmic incompatibility | pt_BR |
| Subject | mosquito control | pt_BR |
| Subject | pathogen blocking | pt_BR |
| Subject | temperature | pt_BR |
