| Author | Hovhannisyan, Lyolya | |
| Author | Coelho, Lara E. | |
| Author | Velasque, Luciane | |
| Author | De Boni, Raquel B. | |
| Author | Clark, Jesse | |
| Author | Cardoso, Sandra W. | |
| Author | Lake, Jordan | |
| Author | Veloso, Valdiléa G. | |
| Author | Grinsztejn, Beatriz | |
| Author | Luz, Paula Mendes | |
| Access date | 2022-07-29T15:49:19Z | |
| Available date | 2022-07-29T15:49:19Z | |
| Document date | 2022 | |
| Citation | HOVHANNISYAN, Lyolya et al. Multilevel Analysis of Individual and Neighborhood Characteristics Associated with Viral Suppression Among Adults with HIV in Rio de Janeiro, Brazil. AIDS and Behavior, v. 26, n. 3, p. 947-962, 2022. | pt_BR |
| ISSN | 1573-3254 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/54075 | |
| Language | eng | pt_BR |
| Publisher | Springer | pt_BR |
| Rights | restricted access | pt_BR |
| Title | Multilevel Analysis of Individual and Neighborhood Characteristics Associated with Viral Suppression Among Adults with HIV in Rio de Janeiro, Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1007/s10461-021-03450-2 | |
| Abstract | Understanding the impact of neighborhood context on viral suppression outcomes may help explain health disparities and identify future interventions. We assessed the relationship between individual characteristics, neighborhood socioeconomic context, and viral suppression using multilevel logistic regression models. Adults with HIV initiating antiretroviral therapy (ART) between 2000 and 2017, who resided in Rio de Janeiro and had an HIV-1 RNA level (viral load) measured 90-270 days after ART initiation were included. Overall, 83.9% achieved viral suppression. Participants who were older, had a higher level of education, and identified as heterosexual cisgender men and cisgender men-who-have-sex-with-men had increased odds of viral suppression. Later calendar year of ART initiation carried the strongest association with viral suppression, reflecting the increased effectiveness and tolerability of ART over time. Neighborhood socioeconomic indicators did not predict viral suppression in unadjusted or adjusted analyses, which may result from the integrated care provided in our health care facility together with Brazil's universal treatment. | pt_BR |
| xmlui.metadata.dc.description.abstractes | Comprender el impacto del contexto representado por el lugar de residencia o vecindario sobre los resultados de supresión viral puede ayudar a explicar las disparidades en salud e identificar futuras intervenciones. Evaluamos la relación entre las características individuales, el contexto socioeconómico del vecindario y la supresión viral utilizando modelos de regresión logística multinivel. Incluimos adultos con VIH que comenzaron terapia antiretroviral (ART) entre los años 2000 y 2017, que residían en Río de Janeiro y tenían un valor de nivel de ARN del VIH-1 (carga viral) medido 90-270 días después del inicio de la ART. En general, el 83.9% logró supresión viral. Los participantes con mayor de edad, mayor nivel de educación, identificados como hombres cisgénero heterosexuales y hombres cisgénero que tienen sexo con hombres tenían mayores probabilidades de supresión viral. Los años calendario más recientes de inicio de ART tuvieron la asociación más fuerte con supresión viral, lo que refleja el incremento de la efectividad y la tolerancia a los antirretrovirales con el paso del tiempo. Los indicadores socioeconómicos del vecindario no predijeron supresión viral en los análisis no ajustados o ajustados, que puede resultar de la atención integrada en nuestro centro de salud junto con el tratamiento universal de Brasil. | pt_BR |
| Affilliation | University of California. South American Program in HIV Prevention Research. Los Angeles, USA / David Geffen School of Medicine at UCLA. Division of Infectious Diseases. Department of Medicine. Los Angeles, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | University of California. South American Program in HIV Prevention Research. Los Angeles, USA / David Geffen School of Medicine at UCLA. Division of Infectious Diseases. Department of Medicine. Los Angeles, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | University of California. South American Program in HIV Prevention Research. Los Angeles, USA / McGovern Medical School at University of Texas Health Science Center at Houston. Division of Infectious Diseases. Department of Medicine. Houston, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | ART | pt_BR |
| Subject | Brazil | pt_BR |
| Subject | HIV/AIDS | pt_BR |
| Subject | LMIC | pt_BR |
| Subject | Neighborhood characteristics | pt_BR |
| Subject | Viral suppression | pt_BR |
