| Author | Silva, Reyllane Carvalho | |
| Author | Silva, Rosa Cristina Ribeiro da | |
| Author | Cruz, Léo Nava Piorsky Dominic | |
| Author | Oliveira, Maxcilene da Silva de | |
| Author | Amoedo, Pedro Marinho | |
| Author | Rebêlo, José Manuel Macário | |
| Author | Silva, Antonia Suely Guimarães e | |
| Author | Pinheiro, Valéria Cristina Soares | |
| Access date | 2022-08-07T14:13:58Z | |
| Available date | 2022-08-07T14:13:58Z | |
| Document date | 2022 | |
| Citation | SILVA, Reyllane Carvalho et al. Predominance of Leishmania (Leishmania) amazonensis DNA in Lutzomyia longipalpis sand flies (Diptera: Psychodidae) from an endemic area for leishmaniasis in Northeastern Brazil. Revista do Instituto de Medicina Tropical de São Paulo, v. 64, e 32, p. 1 - 10., Mar. 2022. | pt_BR |
| ISSN | 1678-9849 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/54484 | |
| Language | eng | pt_BR |
| Publisher | Instituto de Medicina Tropical de São Paulo. | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Flebotomíneos | pt_BR |
| Subject in Portuguese | Doenças parasitárias infecciosas | pt_BR |
| Subject in Portuguese | Parasitas | pt_BR |
| Subject in Portuguese | Biologia molecular | pt_BR |
| Title | Predominance of Leishmania (Leishmania) amazonensis DNA in Lutzomyia longipalpis sand flies (Diptera: Psychodidae) from an endemic area for leishmaniasis in Northeastern Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1590/S1678-9946202264032 | |
| Abstract | Leishmaniasis is a serious public health concern in the Northeastern region of Brazil,
where the sand fly fauna is well studied, although few species have been identified as
competent vectors. The detection of Leishmania spp. parasites in wild-caught sand flies
could help sanitary authorities draw strategies to avoid the transmission of the parasites and,
therefore, the incidence of leishmaniases. We detected Leishmania DNA in wild-caught sand
flies and correlated that data with aspects of sand fly ecology in the Caxias municipality,
Maranhao State, Brazil. The sand flies were sampled in the peridomicile (open areas in the
vicinity of human residences) and intradomicile (inside the residences) from July/2019 to
March/2020. Leishmania DNA was detected in females, targeting a fragment of the Internal
Transcribed Spacer (ITS1) from ribosomal DNA. Among the fourteen species of sand
flies identified, five (Lutzomyia longipalpis, Nyssomyia whitmani, Evandromyia evandroi,
Micropygomyia trinidadensis, and Micropygomyia quinquefer) harbored DNA of Leishmania
(Leishmania) amazonensis. The most abundant species in rural (Ny. whitmani: 35.2% and
Ev. evandroi: 32.4%) and urban areas (Lu. longipalpis: 89.8%) are the permissive vectors
of L. (L.) amazonensis, especially Ny. whitmani, a known vector of causative agents of
cutaneous leishmaniasis. Although Lu. longipalpis is the vector of L. (L.) infantum, which
was not detected in this study, its permissiveness for the transmission of L. (L.) amazonensis
has been reported. We suspect that visceral leishmaniasis and cutaneous leishmaniasis are
caused by L. (L.) amazonensis, and the transmission may be occurring through Lu. longipalpis,
at least in the urban area. | pt_BR |
| Affilliation | Universidade Estadual do Maranhão. Programa de Pós-Graduação em Biodiversidade, Ambiente e Saúde. Laboratório de Entomologia Médica, Caxias, MA, Brasil. | pt_BR |
| Affilliation | Universidade Estadual do Maranhão. Programa de Pós-Graduação em Biodiversidade, Ambiente e Saúde. Laboratório de Entomologia Médica, Caxias, MA, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Estadual do Maranhão. Programa de Pós-Graduação em Biodiversidade e Biotecnologia. Laboratório de Entomologia Médica. Caxias, MA, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Amazonas. Unidade Acadêmica de Parintins. Parintins, AM, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Maranhão. Laboratório de Entomologia e Vetores. São Luís, MA, Brasil. | pt_BR |
| Affilliation | Universidade Estadual do Maranhão. Programa de Pós-Graduação em Biodiversidade, Ambiente e Saúde. Laboratório de Entomologia Médica, Caxias, MA, Brasil. | pt_BR |
| Affilliation | Universidade Estadual do Maranhão. Programa de Pós-Graduação em Biodiversidade, Ambiente e Saúde. Laboratório de Entomologia Médica, Caxias, MA, Brasil. | pt_BR |
| Subject | Phlebotomines | pt_BR |
| Subject | Infectious parasitic diseases | pt_BR |
| Subject | Parasites | pt_BR |
| Subject | Molecular biology | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
