| Author | Medeiros, Maurício Z. | |
| Author | Soares, Priscila F. | |
| Author | Fialho, Beatriz C. | |
| Author | Gauss, Leandro | |
| Author | Piran, Fábio S. | |
| Author | Lacerda, Daniel P. | |
| Access date | 2022-10-10T17:12:50Z | |
| Available date | 2022-10-10T17:12:50Z | |
| Document date | 2022 | |
| Citation | MEDEIROS, Maurício Z. et al. Vaccine innovation model: a technology transfer perspective in pandemic contexts. Vaccine, v. 40, n. 33, p. 4748-4763, 5 Aug. 2022. | en_US |
| ISSN | 0264-410X | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/55086 | |
| Language | eng | en_US |
| Publisher | Elsevier | en_US |
| Rights | open access | en_US |
| Title | Vaccine innovation model: a technology transfer perspective in pandemic contexts | en_US |
| Type | Article | en_US |
| DOI | 10.1016/j.vaccine.2022.06.054 | |
| Abstract | This work identifies the innovations that made it possible for the Bio-Manguinhos/Fiocruz Immunobiological Technology Institute to engage in the entire production of the Oxford/AstraZeneca vaccine (ChAdOx1 nCov-19) in Brazil, just 1.8 years after the COVID-19 pandemic was declared. The results were summarized in a case-based innovation model composed of 11 workstreams, 32 stages, 22 gates, 11 innovations, and 38 events. In terms of research contributions, three were found: (i) the identification of firm and government-level innovations allowing the substantial reduction in the COVID-19 vaccine timeto-market in Brazil; (ii) the presentation of empirical evidence supporting the new Outbreak Paradigm for vaccine research, development, and production; and (iii) the proposition of a conceptual model for describing innovations through the vaccine value chain in pandemic contexts, particularly when technology transfer is involved. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Universidade do Vale do Rio dos Sinos – Unisinos. São Leopoldo, RS, Brasil. | en_US |
| Affilliation | Universidade do Vale do Rio dos Sinos – Unisinos. São Leopoldo, RS, Brasil. | en_US |
| Affilliation | Universidade do Vale do Rio dos Sinos – Unisinos. São Leopoldo, RS, Brasil. | en_US |
| Subject | Vaccine | en_US |
| Subject | Innovation | en_US |
| Subject | Research and development | en_US |
| Subject | COVID-19 | en_US |
| e-ISSN | 0264-410X | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
