| Author | Leandro, André de Souza | |
| Author | Lopes, Renata Defante | |
| Author | Martins, Caroline Amaral | |
| Author | Delai, Robson Michael | |
| Author | Villela, Daniel A. M. | |
| Author | Freitas, Rafael Maciel de | |
| Access date | 2022-11-09T18:26:14Z | |
| Available date | 2022-11-09T18:26:14Z | |
| Document date | 2022 | |
| Citation | LEANDRO, André de Souza et al. Entomo-virological surveillance followed by serological active survey of symptomatic individuals is helpful to identify hotspots of early arbovirus transmission. Frontiers in Public Health, v. 10, 1024187, p. 1 - 9, Oct. 2022. | en_US |
| ISSN | 2296-2565 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/55561 | |
| Language | eng | en_US |
| Publisher | Frontiers Media | en_US |
| Rights | open access | |
| Subject in Portuguese | Vigilância entomovirológica | en_US |
| Subject in Portuguese | Dengue | en_US |
| Subject in Portuguese | Chikungunya | en_US |
| Subject in Portuguese | Sistema de alerta antecipado | en_US |
| Subject in Portuguese | Aedes aegpyti | en_US |
| Subject in Portuguese | Doenças transmitidas por vetores | en_US |
| Subject in Portuguese | Controle de vetores | en_US |
| Subject in Portuguese | Risco de transmissão | en_US |
| Title | Entomo-virological surveillance followed by serological active survey of symptomatic individuals is helpful to identify hotspots of early arbovirus transmission | en_US |
| Type | Article | |
| DOI | 10.3389/fpubh.2022.1024187 | |
| Abstract | Arboviruses transmitted by Aedes aegypti in urban environments have spread
rapidly worldwide, causing great impacts on public health. The development
of reliable and timely alert signals is among the most important steps in
designing accurate surveillance systems for vector-borne diseases. In July and
September 2017, we conducted a pilot study to improve an existing integrated
surveillance systemby using entomo-virological surveillance to prioritize areas
to conduct active searches for individuals with arbovirus infection symptoms.
Foz do Iguaçu City has a permanent entomo-virological surveillance system
with approximately 3,500 traps to capture Aedes sp. in the adult stage. The
Aedes aegypti females are captured alive and human samples are submitted
to RT-qPCR (real-time qPCR) screening for DENV, ZIKV, and CHIKV diagnosis.
Of the 55 Ae. aegypti mosquitoes tested in July 2017, seven (12.7%) were
considered positive for DENV-2 and three (5.4%) for CHIKV. In September, we
tested a sample of 54 mosquitoes, and 15 (27.7%) were considered infected by
DENV-2. We created 25 circumferences with 150-m radius each to perform
an active survey to identify symptomatic householders. In July, we selected
one circumference, and five (35.7%) patients were positive for DENV, whereas
two (14.3%) for CHIKV. In September, we selected four circumferences,
and, from the 21 individuals sampled, nine (42.8%) were positive for DENV-
2. A statistical model with a binomial response was used to estimate the
number of cases in areas without active surveys, i.e., 20 circumferences.
We estimated an additional 83 symptomatic patients (95% CI: 45–145) to
be found in active searches, with 38 (95% CI: 18–72) of them confirming arbovirus infection. Arbovirus detection and serotyping inmosquitoes, but also
in symptomatic individuals during active surveys, can provide an alert signal of
early arbovirus transmission. | en_US |
| Affilliation | Secretaria Municipal de Saúde de Foz do Iguaçu. Centro de Controle de Zoonoses. Foz do Iguaçu, PR, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Secretaria Municipal de Saúde de Foz do Iguaçu. Centro de Controle de Zoonoses. Foz do Iguaçu, PR, Brasil / Universidade Federal Latino-Americana. The Instituto Latino-Americano de Economia, Sociedade e Política. Foz do Iguaçu. Paraná, Brasil. | en_US |
| Affilliation | Secretaria Municipal de Saúde de Foz do Iguaçu. Centro de Controle de Zoonoses. Foz do Iguaçu, PR, Brasil | en_US |
| Affilliation | One Health Laboratory at the Three-Border Tropical Medicine Center, Itaiguapy Foundation - Institute of Teaching and Research. Foz do Iguaçu, PR, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil / Department of Arbovirology, Bernhard Nocht Institute for Tropical Medicine. Hamburg, Germany. | en_US |
| Subject | Entomo-virological surveillance | en_US |
| Subject | Dengue | en_US |
| Subject | Chikungunya | en_US |
| Subject | Early-warning system | en_US |
| Subject | Aedes aegpyti | en_US |
| Subject | Vector-borne diseases | en_US |
| Subject | Vector control | en_US |
| Subject | Transmission risk | en_US |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
