| Author | Escolà-Vergé, Laura | |
| Author | Rello, Pau | |
| Author | Declerck, Charles | |
| Author | Dubée, Vincent | |
| Author | Rouleau, Fréderic | |
| Author | Duval, Xavier | |
| Author | Habib, Gilbert | |
| Author | Lavie-Badie, Yoan | |
| Author | Martin-Blondel, Guillaume | |
| Author | Porte, Lydie | |
| Author | Bouiller, Kevin | |
| Author | Goehringer, François | |
| Author | Selton-Suty, Christine | |
| Author | Lamas, Cristiane da Cruz | |
| Author | Nacinovich, Francisco | |
| Author | Issa, Nahema | |
| Author | Richaud, Clémence | |
| Author | Hammoudi, Nadjib | |
| Author | Barranco, Francisco José | |
| Author | Almirante, Benito | |
| Author | Tattevin, Pierre | |
| Author | Fernández-Hidalgo, Nuria | |
| Access date | 2022-12-11T14:42:25Z | |
| Available date | 2022-12-11T14:42:25Z | |
| Document date | 2022 | |
| Citation | ESCOLÀ-VERGÉ, Laura et al. Infective endocarditis in pregnant women without intravenous drug use: a multicentre retrospective case series. The Journal of antimicrobial chemotherapy, v. 77, n. 10, p. 2701-2705, Sept. 2022. | en_US |
| ISSN | 0305-7453 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/55912 | |
| Sponsorship | This work was carried out as part of our routine work. Laura Escolà-Vergé has a Juan Rodés contract in the call 2020 Strategic Action Health from Instituto de Salud Carlos III of Spanish Health Ministry for the years 2021–24 (JR20/00020). | |
| Language | eng | en_US |
| Publisher | Oxford | en_US |
| Rights | open access | en_US |
| Title | Infective endocarditis in pregnant women without intravenous drug use: a multicentre retrospective case series | en_US |
| Type | Article | en_US |
| DOI | 10.1093/jac/dkac258 | |
| Abstract | Objectives: To describe the clinical features and outcomes of infective endocarditis (IE) in pregnant women who do not inject drugs. Methods: A multinational retrospective study was performed at 14 hospitals. All definite IE episodes between January 2000 and April 2021 were included. The main outcomes were maternal mortality and pregnancy-related complications. Results: Twenty-five episodes of IE were included. Median age at IE diagnosis was 33.2 years (IQR 28.3-36.6) and median gestational age was 30 weeks (IQR 16-32). Thirteen (52%) patients had no previously known heart disease. Sixteen (64%) were native IE, 7 (28%) prosthetic and 2 (8%) cardiac implantable electronic device IE. The most common aetiologies were streptococci (n = 10, 40%), staphylococci (n = 5, 20%), HACEK group (n = 3, 12%) and Enterococcus faecalis (n = 3, 12%). Twenty (80%) patients presented at least one IE complication; the most common were heart failure (n = 13, 52%) and symptomatic embolism other than stroke (n = 4, 16%). Twenty-one (84%) patients had surgery indication and surgery was performed when indicated in 19 (90%). There was one maternal death and 16 (64%) patients presented pregnancy-related complications (11 patients ≥1 complication): 3 pregnancy losses, 9 urgent Caesarean sections, 2 emergency Caesarean sections, 1 fetal death, and 11 preterm births. Two patients presented a relapse during a median follow-up of 3.1 years (IQR 0.6-7.4). Conclusions: Strict medical surveillance of pregnant women with IE is required and must involve a multidisciplinary team including obstetricians and neonatologists. Furthermore, the potential risk of IE during pregnancy should never be underestimated in women with previously known underlying heart disease. | en_US |
| Affilliation | Universitat Autònoma de Barcelona. Hospital Universitari Vall d'Hebron. Servei de Malalties Infeccioses. Barcelona, Spain / Instituto de Salud Carlos III. ISCIII-CIBER de Enfermedades Infecciosas. Madrid, Spain. | en_US |
| Affilliation | Hospital Universitari Vall d'Hebron. Department of Cardiology. Barcelona, Spain. | en_US |
| Affilliation | Angers University Hospital. Infectious Diseases Department. Angers, France. | en_US |
| Affilliation | Angers University Hospital. Infectious Diseases Department. Angers, France. | en_US |
| Affilliation | Angers University Hospital. Department of Cardiology. Angers, France. | en_US |
| Affilliation | Paris Cité University. Bichat Hospital, Infectious Diseases. Paris, France. | en_US |
| Affilliation | Aix Marseille University. La Timone Hospital. Cardiology Department. Marseille, France. | en_US |
| Affilliation | Toulouse University Hospital. Heart Valve Center. Toulouse, France. | en_US |
| Affilliation | Toulouse University Hospital. Department of Infectious and Tropical Diseases. Toulouse, France. | en_US |
| Affilliation | Toulouse University Hospital. Department of Infectious and Tropical Diseases. Toulouse, France. | en_US |
| Affilliation | CHU Besancon. Infectious Diseases. Besancon, France. | en_US |
| Affilliation | Nancy University Hospital. Infectious Diseases Department. Nancy, France. | en_US |
| Affilliation | CHU Nancy. Cardiology Department. Nancy, France. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Unigranrio. Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Instituto Cardiovascular Buenos Aires. Infectious Diseases. Buenos Aires, Argentina. | en_US |
| Affilliation | University Hospital. Groupe Saint-André Hospital. Infectious Diseases and ICU. Bordeaux, France. | en_US |
| Affilliation | Institut Mutualiste Montsouris. Internal Medecine. Paris, France. | en_US |
| Affilliation | Sorbonne Université. ACTION Study Group. Paris, France / Hôpital Pitié-Salpêtrière. Paris, France. | en_US |
| Affilliation | Universitat Autònoma de Barcelona. Vall d'Hebron Barcelona Hospital Campus. Department of Obstetrics. Maternal Fetal Medicine Unit. Barcelona, Spain. | en_US |
| Affilliation | Universitat Autònoma de Barcelona. Hospital Universitari Vall d'Hebron. Servei de Malalties Infeccioses. Barcelona, Spain / Instituto de Salud Carlos III. ISCIII-CIBER de Enfermedades Infecciosas. Madrid, Spain. | en_US |
| Affilliation | Pontchaillou University Hospital. Infectious Diseases and ICU. Rennes, France. | en_US |
| Affilliation | Universitat Autònoma de Barcelona. Hospital Universitari Vall d'Hebron. Servei de Malalties Infeccioses. Barcelona, Spain / Instituto de Salud Carlos III. ISCIII-CIBER de Enfermedades Infecciosas. Madrid, Spain. | en_US |
| Subject | Infective endocarditis | en_US |
| Subject | Pregnant women | en_US |
| Subject | Heart disease | en_US |
| e-ISSN | 1460-2091 | |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
