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| Autor | Assis, Jéssica Vieira de | |
| Autor | Coutinho, Lucélia Antunes | |
| Autor | Oyeyemi, Ifeoluwa Temitayo | |
| Autor | Oyeyemi, Oyetunde Timothy | |
| Autor | Queiroz, Rafaella Fortini Grenfell e | |
| Fecha de acceso | 2022-12-20T12:18:42Z | |
| Fecha de disponibilización | 2022-12-20T12:18:42Z | |
| Fecha de publicación | 2022 | |
| Referencia | ASSIS, Jéssica Vieira de et al. Diagnostic and therapeutic biomarkers in colorectal cancer: a review. Am J Cancer Res., v. 12, n. 2, p. 661-680. | en_US |
| ISSN | 2156-6976 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/56077 | |
| Idioma | eng | en_US |
| Editor | e-Century Pub. Corp. | en_US |
| Derechos de autor | open access | en_US |
| Título | Diagnostic and therapeutic biomarkers in colorectal cancer: a review | en_US |
| Tipo del documento | Article | en_US |
| Resumen en Inglés | Colorectal cancer (CRC) is a public health concern and the second most common type of cancer among men and women causing a significant mortality. Biomarkers closely linked to the disease morbidity could holds potential as diagnostic and/or prognostic biomarker for the disease. This review provides an overview of recent advances in the search for colorectal cancer biomarkers through genomics and proteomics according to clinical function and application. Specifically, a number of biomarkers were identified and discussed. Emphasis was placed on their clinical applications relative to the diagnosis and prognosis of CRC. The discovery of more sensitive and specific markers for CRC is an urgent need, and the study of molecular targets is extremely important in this process, as they will allow for a better understanding of colorectal carcinogenesis, identification and validation of potential genetic signatures. | en_US |
| Afiliación | Diagnosis and Therapy of Infectious Diseases and Cancer. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil. | en_US |
| Afiliación | Diagnosis and Therapy of Infectious Diseases and Cancer. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil. | en_US |
| Afiliación | Department of Biological Sciences. University of Medical Sciences Ondo. Ondo State, Nigeria. | en_US |
| Afiliación | Diagnosis and Therapy of Infectious Diseases and Cancer. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil/Department of Biological Sciences. University of Medical Sciences Ondo. Ondo State, Nigeria. | en_US |
| Afiliación | Diagnosis and Therapy of Infectious Diseases and Cancer. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil/Department of Infectious Diseases. College of Veterinary Medicine. University of Georgia Athens. Georgia, United States of America. | en_US |
| Palavras clave en Inglês | Biomarkers | en_US |
| Palavras clave en Inglês | colorectal cancer | en_US |
| Palavras clave en Inglês | management | en_US |
| Palavras clave en Inglês | prognosis | en_US |
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