| Author | Ferri, Lucila Pessuti | |
| Author | Junqueira, Priscilla dos Santos | |
| Author | Almeida, Mayara Maria Souza de | |
| Author | Oliveira, Mariana Gomes | |
| Author | Oliveira, Brunna Rodrigues de | |
| Author | Silva, Bruno Vinícius Diniz e | |
| Author | Magalhães, Larissa Silva | |
| Author | Villar, Lívia Melo | |
| Author | Caetano, Karlla Antonieta Amorim | |
| Author | Souza, Márcia Maria | |
| Author | Carneiro, Megmar Aparecida dos Santos | |
| Author | Martins, Regina Maria Bringel | |
| Author | Teles, Sheila Araujo | |
| Access date | 2023-01-10T11:24:16Z | |
| Available date | 2023-01-10T11:24:16Z | |
| Document date | 2022 | |
| Citation | FERRI, Lucila Pessuti et al. Viral Hepatitis A, B and C in a Group of Transgender Women in Central Brazil. Tropical Medicine and Infectious Disease, v. 7, 269, p. 1 - 11, Sept. 2022. | en_US |
| ISSN | 2414-6366 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/56416 | |
| Language | eng | en_US |
| Publisher | MDPI | en_US |
| Rights | open access | |
| Subject in Portuguese | Hepatite A | en_US |
| Subject in Portuguese | Hepatite B | en_US |
| Subject in Portuguese | Hepatite C | en_US |
| Subject in Portuguese | Imunogenicidade | en_US |
| Subject in Portuguese | Mulheres transexuais | en_US |
| Subject in Portuguese | Vacinação | en_US |
| Subject in Portuguese | Hepatite viral | en_US |
| Title | Viral Hepatitis A, B and C in a Group of Transgender Women in Central Brazil | en_US |
| Type | Article | |
| DOI | 10.3390/ tropicalmed7100269 | |
| Abstract | Transgender women (TGW) have limited access to affordable viral hepatitis testing, hepatitis
B vaccination, and treatment. We aimed to estimate the prevalence of viral hepatitis A, B, and
C, as well as to compare the adherence and immunogenicity of two hepatitis B vaccine schedules
among TGW in Central Brazil. A total of 440 TGW were interviewed and tested for hepatitis A, B,
and C serological markers from 2017 to 2018. The hepatitis B vaccine was offered to 230 eligible TGW:
112 received a super accelerated hepatitis B vaccine schedule (G1) and 118 a standard schedule (G2).
The antibody against the hepatitis A virus (HAV) was detected in 75.63% of the participants, and
12.3% of the TGW were exposed to the hepatitis B virus (HBV). Two (0.46%) participants were HBV
carriers. Only 41.5% of the participants showed a serological profile of hepatitis B vaccination. The
antibody against the hepatitis C virus (anti-HCV) was found in six participants (1.37%). Of the TGW
who received the first vaccine dose, 62 (55.36%) and 49 (41.52%) in G1 and G2, respectively, received
three doses (p = 0.036). The vaccine response was evaluated in 28 G1 and 22 G2 TGW; of these,
89.3% and 100% developed protective anti-hepatitis B surface-antigen titers, respectively (p = 0.113).
Since one-third of younger transgender women are susceptible to HAV, hepatitis B immunization is
low, and the anti-HCV rate is higher in this group than in the general population in Central Brazil,
public-health attention is warranted. The super-accelerated scheme demonstrated better adhesion
and good immunogenicity, suggesting that it would be a more cost-effective solution. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatities Virais. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Instituto de Patologia Tropical e Saúde Pública. Goiânia, GO, Brasil. | en_US |
| Affilliation | Universidade Federal de Goiás. Faculdade de Enfermagem. Gioânia, GO, Brasil. | en_US |
| Subject | Hepatitis A | en_US |
| Subject | Hepatitis B | en_US |
| Subject | Hepatitis C | en_US |
| Subject | Immunogenicity | en_US |
| Subject | Transgender women | en_US |
| Subject | Vaccination | en_US |
| Subject | Viral hepatitis | en_US |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
