| Author | Azevedo, Daniela Castelo | |
| Author | Assunção, Fernando César Menezes | |
| Author | Castro, Mônica Silva Monteiro de | |
| Author | Valle, Estevão Alves | |
| Access date | 2023-02-02T16:16:10Z | |
| Available date | 2023-02-02T16:16:10Z | |
| Document date | 2022 | |
| Citation | AZEVEDO, Daniela Castelo et al. Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study. São Paulo Medical Journal, v. 140, n. 5, p. 676-681, Sept./Oct. 2022. | en_US |
| ISSN | 1516-3180 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/56835 | |
| Language | eng | en_US |
| Publisher | Associação Paulista de Medicina | en_US |
| Rights | open access | en_US |
| MeSH | Frail elderly | en_US |
| MeSH | Hospitalization | en_US |
| MeSH | COVID-19 | en_US |
| MeSH | Risk factors | en_US |
| MeSH | Frailty | en_US |
| Title | Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study | en_US |
| Type | Article | en_US |
| DOI | 10.1590/1516-3180.2021.0649.R1.20122021 | |
| Abstract | Background: Advanced age, multiple chronic diseases and frailty have been correlated with worse prognosis among coronavirus disease 2019 (COVID-19) inpatients. Objective: To investigate potential risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people. Design and setting: Retrospective cohort study of patients followed up at a geriatric outpatient clinic in Belo Horizonte, Minas Gerais, Brazil. Methods: The associations of demographic characteristics (age and sex) and clinical characteristics (frailty, multimorbidity, number of medications with long-term use, obesity, smoking, diabetes mellitus, pulmonary diseases, cardiovascular diseases, cerebrovascular disease, and chronic kidney disease) with the risk of hospitalization and death due to COVID-19 were explored using a multivariable logistic regression model. Results: 5,295 patients (mean age 78.6 ± 9.4 years; 72.6% females) were included. After adjustments, the number of medications with long-term use was found to increase the odds of hospitalization due to COVID-19 (odds ratio, OR: 1.13; 95% confidence interval, CI: 1.06-1.22). Frailty, multimorbidity and diabetes mellitus also increased the odds of hospitalization (OR: 1.06, 95% CI: 1.02-1.09; OR: 1.17, 95% CI: 1.09-1.26; and OR: 2.27, 95% CI: 1.45-3.54, respectively) and the odds of death due to COVID-19 (OR: 1.07, 95% CI: 1.00-1.14; OR: 1.16, 95% CI: 1.03-1.32; and OR: 2.69, 95% CI: 1.79-6.14, respectively). Conclusions: Multimorbidity, frailty and diabetes mellitus increased the odds of hospitalization and death due to COVID-19 and the number of medications with long-term use increased the odds of hospitalization due to COVID-19 among frail community-dwelling elderly people. | en_US |
| Affilliation | Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil. | en_US |
| Affilliation | Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil / LifeCodeTM Information System. Belo Horizonte, MG, Brazil. | en_US |
| Affilliation | Oswaldo Cruz Foundation. René Rachou Institute. Health Policy and Social Protection Research Group. Belo Horizonte, MG, Brazil. | en_US |
| Affilliation | Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil. | en_US |
| Subject | Older adults | en_US |
| Subject | Community-dwelling elderly | en_US |
| Subject | SARS-CoV-2 virus | en_US |
| Subject | COVID-19 | |
