| Author | Soares CRP | |
| Author | Oliveira-Júnior JB | |
| Author | Firmo EF. | |
| Access date | 2023-03-31T15:28:54Z | |
| Available date | 2023-03-31T15:28:54Z | |
| Document date | 2020 | |
| Citation | Soares CRP, Oliveira-Júnior JB, Firmo EF. First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil. Rev Soc Bras Med Trop. 2020. | en_US |
| ISSN | 0037-8682 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/57643 | |
| Language | eng | en_US |
| Rights | restricted access | |
| Title | First report of a blaNDM-resistant gene in a Klebsiella aerogenes clinical isolate from Brazil | en_US |
| Type | Article | |
| DOI | 10.1590/0037-8682-0262-2020 | |
| Abstract | Carbapenemase-resistant enterobacteria that produce the blaNDM gene are found worldwide. However, this is the first
report of blaNDM in Klebsiella aerogenes in Brazil. Methods: The identification of bacterial species was performed using anautomated
system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes. Results: The clinical isolate
showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the
blaNDM gene was detected. Conclusions: The current report of the bla NDM gene in isolated MDR enterobacteria indicates that this gene
can spread silently in a hospital setting. | en_US |
| Affilliation | Universidade Federal de Pernambuco, Departamento de Medicina Tropical, Recife, PE, Brasil.
Fundação, Oswaldo Cruz, Instituto Aggeu Magalhães, Laboratório de Biologia Molecular e Celular, Departamento de Parasitologia, Recife, PE, Brasil. | |
| Subject | Klebsiella aerogenes | en_US |
| Subject | blaNDM gene | en_US |
| Subject | metallo-betalactamase | en_US |
| Subject | Carbapenemase | en_US |
| Subject | Multidrug-resistant | en_US |
