| Author | Menezes, Graciéle Cunha Alves de | |
| Author | Porto, Bárbara Alves | |
| Author | Amorim, Soraya Sander | |
| Author | Zani, Carlos Leomar | |
| Author | Alves, Tânia Maria de Almeida | |
| Author | Sales Junior, Policarpo Ademar | |
| Author | Murta, Silvane Maria Fonseca | |
| Author | Simões, Jefferson Cardia | |
| Author | Cota, Betania Barros | |
| Author | Rosa, Carlos Augusto | |
| Author | Rosa, Luiz Henrique | |
| Access date | 2023-05-16T12:02:31Z | |
| Available date | 2023-05-16T12:02:31Z | |
| Document date | 2020 | |
| Citation | MENEZES, Graciéle Cunha Alves de et al. Fungi in glacial ice of Antarctica: diversity, distribution and bioprospecting of bioactive compounds. Extremophiles, v. 24, p. 367–376, 2020. https://doi.org/10.1007/s00792-020-01161-5 | en_US |
| ISSN | 1431-0651 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/58422 | |
| Language | eng | en_US |
| Publisher | Springer | en_US |
| Rights | restricted access | |
| Subject in Portuguese | Antarctica | en_US |
| Subject in Portuguese | gelo | en_US |
| Subject in Portuguese | fungo | en_US |
| Title | Fungi in glacial ice of Antarctica: diversity, distribution and bioprospecting of bioactive compounds | en_US |
| Type | Article | |
| DOI | 10.1007/s00792-020-01161-5 | |
| Abstract | We identified cultivable fungi present in the glacial ice fragments collected in nine sites across Antarctica Peninsula and assessed their abilities to produce bioactive compounds. Three ice fragments with approximately 20 kg were collected, melted and 3 L filtered through of 0.45 mu m sterilized membranes, which were placed on the media Sabouraud agar and minimal medium incubated at 10 degrees C. We collected 66 isolates classified into 27 taxa of 14 genera. Penicillium palitans, Penicillium sp. 1, Thelebolus balaustiformis, Glaciozyma antarctica, Penicillium sp. 7, Rhodotorula mucilaginosa, and Rhodotorula dairenensis had the highest frequencies. The diversity and richness of the fungal community were high with moderate dominance. Penicillium species were present in all samples, with Penicillium chrysogenum showing the broadest distribution. P. chrysogenum, P. palitans, and Penicillium spp. had trypanocidal, leishmanicidal, and herbicidal activities, with P. chrysogenum having the broadest and highest capability. H-1 NMR signals revealed the presence of highly functionalized secondary metabolites in the bioactive extracts. Despite extreme environmental conditions, glacial ice harbours a diverse fungal community, including species never before recorded in the Arctic and Antarctica. Among them, Penicillium taxa may represent wild fungal strains with genetic and biochemical pathways that may produce new secondary bioactive metabolites. | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Universidade Federal do Rio Grande do Sul. Centro Polar e Climático. Porto Alegre, RS, Brazil | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil | en_US |
| Affilliation | Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brazil | en_US |
| Subject | Antarctica | en_US |
| Subject | Ice | en_US |
| Subject | Fungi | en_US |
| Subject | Secondary metabolites | en_US |
| Embargo date | 2099-12-31 | |
