| Author | Badaró, Roberto | |
| Author | Novaes, Gustavo | |
| Author | Andrade, Ana Cristina | |
| Author | Araujo Neto, Cesar Augusto de | |
| Author | Machado, Bruna Aparecida | |
| Author | Barbosa, Josiane Dantas Viana | |
| Author | Soares, Milena Botelho Pereira | |
| Access date | 2023-06-06T18:31:13Z | |
| Available date | 2023-06-06T18:31:13Z | |
| Document date | 2023 | |
| Citation | BADARÓ, Roberto et al. Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine. Frontiers in Medicine, v. 10, p. 1-6, 2023. | en_US |
| ISSN | 2296-858X | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/58957 | |
| Sponsorship | Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde, Centro Universitário.
Conselho Nacional do Brasil (CNPq). | en_US |
| Language | eng | en_US |
| Publisher | Frontiers Media | en_US |
| Rights | open access | en_US |
| Subject in Portuguese | COVID-19 | en_US |
| Subject in Portuguese | Vacina mRNA | en_US |
| Subject in Portuguese | Cardiotoxicidade | en_US |
| Subject in Portuguese | Doença cardíaca | en_US |
| Subject in Portuguese | Evento adverso | en_US |
| Title | Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine | en_US |
| Type | Article | en_US |
| DOI | 10.3389/fmed.2023.1071239 | |
| Abstract | A 23-year-old man started with chest pain 8 h after his first Pfizer-BioNTech COVID 19 vaccination. ECG evaluation showed sinus tachycardia with ST-segment elevation in D1, AVL, V5, and V6, the findings compatible with acute subepicardial myocardial damage. However, cardiac MRI documented myocardial fibrosis, with cardiac late enhancement non-ischemic pattern with diffuse edema. He had no other symptoms to suggest another etiology than the vaccination. The patient was hospitalized and received corticosteroid (prednisolone) daily. Then, 2 weeks after hospitalization, all laboratory parameters and ECG were normal and the patient was discharged from the hospital. The patient had a history of Wolf-Parkinson White that was corrected with ablation when he was 11 years old. This report calls attention to myocardial adverse reaction risk for mRNA COVID-19 vaccines for people with a previous cardiac
disease history. | en_US |
| Affilliation | Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil / Clínica Especializada Allmed. Salvador, BA, Brasil. | en_US |
| Affilliation | Hospital UNIMED. Feira de Santana, BA, Brasil. | en_US |
| Affilliation | Clínica Especializada Allmed. Salvador, BA, Brasil. | en_US |
| Affilliation | Diagnóstico por Imagem, Salvador, BA, Brasil. | en_US |
| Affilliation | Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil. | en_US |
| Affilliation | Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil. | en_US |
| Affilliation | Centro Universitário SENAI/CIMATEC. Instituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | en_US |
| Subject | COVID-19 | en_US |
| Subject | mRNA vaccine | en_US |
| Subject | Cardiotoxicity | en_US |
| Subject | Cardiac disease | en_US |
| Subject | Adverse event | en_US |
| DeCS | COVID-19 | en_US |
| DeCS | Vacina de mRNA-1273 contra 2019-nCoV | en_US |
| DeCS | Cardiotoxicidade | en_US |
| DeCS | Doenças Cardiovasculares | en_US |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
