| Autor | Jacques, Iracema J. A. A. | |
| Autor | Katz, Leila | |
| Autor | Sena, Marília A. | |
| Autor | Guimarães, Ana B. G. | |
| Autor | Silva, Yasmim L. | |
| Autor | Albuquerque, Gabriela D. M. | |
| Autor | Pereira, Raisa O. | |
| Autor | Albuquerque, Camila A. M. C. de | |
| Autor | Silva, Maria Almerice L. | |
| Autor | Oliveira, Paula A. S. | |
| Autor | Albuquerque, Maria de Fátima P. M. | |
| Autor | Cordeiro, Marli T. | |
| Autor | Marques, Ernesto T. A. Jr | |
| Autor | França, Rafael F. O. | |
| Autor | Martelli, Celina M. T. | |
| Autor | Castanha, Priscila M. S. | |
| Autor | Braga, Cynthia | |
| Data de acesso | 2023-06-28T15:04:44Z | |
| Data de disponibilização | 2023-06-28T15:04:44Z | |
| Data do publicação | 2021 | |
| Citação | JACQUES, Iracema J. A. A. et al. High Incidence of Zika or Chikungunya Infection among Pregnant Women Hospitalized Due to Obstetrical Complications in Northeastern Brazil—Implications for Laboratory Screening in Arbovirus Endemic Area. Viruses, [S.l.], v. 13, n. 5, p. 1-14, 23 abr. 2021 | en_US |
| ISSN | 1999-4915 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/59222 | |
| Idioma | por | en_US |
| Direito Autoral | open access | en_US |
| MeSH | Adolescent | en_US |
| MeSH | Adult | en_US |
| MeSH | Brazil / epidemiology | en_US |
| MeSH | Chikungunya Fever / epidemiology* | en_US |
| MeSH | Chikungunya virus* | en_US |
| MeSH | Cross Infection / epidemiology* | en_US |
| MeSH | Cross Infection / virology | en_US |
| MeSH | Disease Susceptibility | en_US |
| MeSH | Female | en_US |
| MeSH | Humans | en_US |
| MeSH | Incidence | en_US |
| MeSH | Middle Aged | en_US |
| MeSH | Pregnancy | en_US |
| MeSH | Pregnancy Complications, Infectious / epidemiology* | en_US |
| MeSH | Pregnancy Complications, Infectious / virology | en_US |
| MeSH | Prospective Studies | en_US |
| MeSH | Public Health Surveillance | en_US |
| MeSH | Risk Factors | en_US |
| MeSH | Young Adult | en_US |
| MeSH | Zika Virus Infection / epidemiology* | en_US |
| MeSH | Zika Virus* | en_US |
| Título | High Incidence of Zika or Chikungunya Infection among Pregnant Women Hospitalized Due to Obstetrical Complications in Northeastern Brazil-Implications for Laboratory Screening in Arbovirus Endemic Area | en_US |
| Tipo do documento | Article | en_US |
| DOI | 10.3390/v13050744 | |
| Resumo em Inglês | The diagnostic of arbovirus-related obstetric complications in high-risk pregnancy and childbirth care is challenging, especially in endemic areas. We conducted a prospective study to track active or recent Zika (ZIKV), dengue (DENV), or chikungunya (CHIKV) virus infection among hospitalized pregnant women (PW) with obstetric complications in a hospital at the epicenter of Zika outbreak and ZIKV-related microcephaly in Brazil. Clinical data and blood samples were collected at enrollment and 10 days after the admission of study participants, between October 2018 and May 2019. Further clinical data were extracted from medical records. Samples were screened by molecular and serological tests. Out of 780 participants, 93.1% (95% CI: 91.1-94.7%) presented previous DENV exposure (IgG). ZIKV, CHIKV, and/or DENV laboratory markers of recent or active infection were detected in 130 PW, yielding a prevalence of 16.6% (95% CI: 14.2-19.5%); 9.4% (95% CI: 7.4-11.7%), 7.4% (95% CI: 5.7-9.7%), and 0.38% (95% CI: 0.1-1.2%) of CHIKV, ZIKV, and DENV infections, respectively. Most ZIKV infections were detected by molecular assays (89.6%), while CHIKV infections were detected by serology (95.9%). Our findings highlight the need for arbovirus infections screening in PW with obstetrical complications, potentially associated to these infections in endemic areas regardless of the signs or symptoms suggestive of arboviral disease. | en_US |
| Afiliação | Instituto Aggeu Magalhães. Fundação Oswaldo Cruz Pernambuco. Recife, PE, Brasil. | en_US |
| Afiliação | Instituto de Medicina Integral Prof. Fernando Figueira. Recife, PE, Brasil. | en_US |
| Afiliação | Department of Infectious Diseases and Microbiology. University of Pittsburgh. Pittsburgh, PA, USA. | en_US |
| Afiliação | Faculdade de Ciências Médicas. Universidade de Pernambuco. Recife, PE, Brazil. | en_US |
| Palavras-chave em inglês | Zika virus | en_US |
| Palavras-chave em inglês | chikungunya virus | en_US |
| Palavras-chave em inglês | dengue virus | en_US |
| Palavras-chave em inglês | pregnancy complications | en_US |
| e-ISSN | 1999-4915 | |
