Author | Assunção, Lucimar Gonçalves de Souza | |
Author | Santos, Silvana Maria Elói | |
Author | Peixoto, Sérgio William Viana | |
Access date | 2023-07-11T13:19:43Z | |
Available date | 2023-07-11T13:19:43Z | |
Document date | 2012 | |
Citation | ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012. | en_US |
ISSN | 0100-879X | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/59505 | |
Language | eng | en_US |
Publisher | Associação Brasileira de Divulgação Científica | en_US |
Rights | open access | en_US |
Title | High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil | en_US |
Type | Article | en_US |
DOI | 10.1590/S0100-879X2012007500154 | |
Abstract | The measurement of the serum concentration of the acute-phase reactant C-reactive protein (CRP) provides a useful marker in clinical practice. However, the distribution of CRP is not available for all age and population groups. This study assessed the distribution of high sensitivity CRP (hs-CRP) by gender and age in 1470 elderly individuals from a Brazilian community that participates in the Bambui Cohort Study. Blood samples were collected after 12 h of fasting and serum samples were stored at -70 degrees C. Measurements were made with a commercial hs-CRP immunonephelometric instrument. More than 50% of the results were above 3.0 mg/L for both genders. Mean hs-CRP was higher in women (3.62 +/- 2.58 mg/L) than in men (3.03 +/- 2.50 mg/L). This difference was observed for all ages, except for the over-80 age group. This is the first population-based study to describe hs-CRP values in Latin American elderly subjects. Our results indicate that significant gender differences exist in the distribution of hs-CRP, and suggest that gender-specific cut-off points for hs-CRP would be necessary for the prediction of cardiovascular risks. | en_US |
Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil. | en_US |
Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil / Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Propedêutica Complementar. Belo Horizonte, MG, Brazil. | en_US |
Affilliation | Universidade Federal de Minas Gerais. Escola de Enfermagem. Departamento de Enfermagem Aplicada. Belo Horizonte, MG, Brazil / Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil. | en_US |
Subject | C-reactive protein | en_US |
Subject | Elderly | en_US |
Subject | Epidemiology | en_US |
Subject | Cardiovascular risk | en_US |
Subject | Brazil | en_US |