| Author | Marques, André M. | |
| Author | Provance, D. William | |
| Author | Kaplan, Maria Auxiliadora C. | |
| Author | Figueiredo, Maria Raquel | |
| Access date | 2023-07-18T07:09:09Z | |
| Available date | 2023-07-18T07:09:09Z | |
| Document date | 2017 | |
| Citation | MARQUES, André M. et al. Echinodorus grandiflorus: Ethnobotanical, phytochemical and pharmacological overview of a medicinal plant used in Brazil. Food and Chemical Toxicology, v. 109, n. Pt 2, p. 1032-1047, Nov. 2017. | |
| ISSN | 0278-6915 | |
| URI | https://www.arca.fiocruz.br/handle/icict/59640 | |
| Language | eng | en_US |
| Publisher | Elsevier | |
| Rights | restricted access | |
| MeSH | Alismataceae | en_US |
| MeSH | Animals | en_US |
| MeSH | Anti-Inflammatory Agents | en_US |
| MeSH | Antihypertensive Agents | en_US |
| MeSH | Brazil | en_US |
| MeSH | Humans | en_US |
| MeSH | Phytochemicals | en_US |
| MeSH | Plant Extracts | en_US |
| MeSH | Plants Medicinal | en_US |
| Title | Echinodorus grandiflorus: Ethnobotanical, phytochemical and pharmacological overview of a medicinal plant used in Brazil | en_US |
| Type | Preprint | |
| DOI | 10.1016/J.FCT.2017.03.026 | |
| Abstract | Echinodorus grandiflorus (Cham. & Schltdl.) Micheli is a native Brazilian species used in traditional practices for the treatment of several conditions such as inflammatory diseases, arthritis and hypertension. Through a systematic review of the accumulated knowledge about the species E. grandiflorus, the botanical, phytochemistry, ethnobotanical and pharmacological properties of this medicinal plant demonstrates its potential to naturally provide anti-inflammatory and anti-oxidant with a special emphasis on anti-hypertensive and cardioprotective effects. The body of literature reports that the chemical composition of crude E. grandiflorus extracts are notably composed of diterpenoids and flavonoids metabolites. Pharmacological studies have shown that oral treatments using the hydroalcoholic extracts of leaves from this plant has a significant anti-inflammatory, anti-hypertensive, diuretic and cardioprotective effects in rats with no toxicity. The holistic activities of complex extracts are corroborated by the individuals mechanisms of action, as well as, synergistic benefits attributed to the isolated chemical major constituents in this species. In light of the serious health concerns ascribed, it is important to investigate medicinal plant species with histories of traditional use for circulatory problems to meet the growing demands by scientifically validating their use and safety. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos - Farmanguinhos. Departamento de Produtos Naturais. Laboratório de Produtos Naturais, PN3. Rio de Janeiro, RJ, Brazil. | |
| Affilliation | Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brazil. | |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Pesquisas de Produtos Naturais Walter Mors. Rio de Janeiro, RJ, Brazil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos - Farmanguinhos. Departamento de Produtos Naturais. Laboratório de Produtos Naturais, PN3. Rio de Janeiro, RJ, Brazil. | |
| Subject | Echinodorus grandiflorus | en_US |
| Subject | Ethnobotanical | en_US |
| Subject | Phytochemical | en_US |
| Subject | Pharmacological | en_US |
| Subject | Echinodorus grandiflorus | en_US |
| Subject | Endothelial dysfunction | en_US |
| Subject | Antihypertensive agents | en_US |
| Subject | Anti-inflammatory agents | en_US |
| Subject | Chapeu de couro | en_US |
| Subject | Aspalathus-linearis | en_US |
| Subject | Anti-hypertensive | en_US |
| Subject | Phytochemicals | en_US |
| e-ISSN | 1873-6351 | |
| Embargo date | 2030-12-31 | |
