| Author | Paula, André Guilherme Portela de | |
| Author | Lima, Jordana Dinorá de | |
| Author | Bastos, Thais Sibioni Berti | |
| Author | Czaikovski, Andressa Pacheco | |
| Author | Luz, Rebeca Bosso dos Santos | |
| Author | Yuasa, Bruna Sadae | |
| Author | Smanioto, Caio Cesar Souza | |
| Author | Robert, Anny Waloski | |
| Author | Braga, Tárcio Teodoro | |
| Access date | 2023-07-21T17:16:56Z | |
| Available date | 2023-07-21T17:16:56Z | |
| Document date | 2023 | |
| Citation | PAULA, André Guilherme Portela de et al. Decellularized extracellular matrix: the role of this complex biomaterial in regeneration. ACS Omega, v. 8, n. 25, p. 22256-22267, Jun. 2023. | en_US |
| ISSN | 2470-1343 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/59716 | |
| Language | por | en_US |
| Publisher | American Chemical Society | en_US |
| Rights | open access | en_US |
| Title | Decellularized extracellular matrix: the role of this complex biomaterial in regeneration | en_US |
| Type | Article | en_US |
| DOI | 10.1021/acsomega.2c06216 | |
| Abstract | Organ transplantation is understood as a technique where an organ from a donor patient is transferred to a recipient patient. This practice gained strength in the 20th century and ensured advances in areas of knowledge such as immunology and tissue engineering. The main problems that comprise the practice of transplants involve the demand for viable organs and immunological aspects related to organ rejection. In this review, we address advances in tissue engineering for reversing the current challenges of transplants, focusing on the possible use of decellularized tissues in tissue engineering. We address the interaction of acellular tissues with immune cells, especially macrophages and stem cells, due to their potential use in regenerative medicine. Our goal is to exhibit data that demonstrate the use of decellularized tissues as alternative biomaterials that can be applied clinically as partial or complete organ substitutes. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Biologia Básica de Células Tronco. Curitiba, PR, Brasil. | en_US |
| Affilliation | Universidade Federal do Paraná. Departamento de Patologia. Curitiba, PR, Brasil. / Fundação Oswaldo Cruz. Instituto Carlos Chagas. Programa de Pós-Graduação em Biociências e Biotecnologia. Curitiba, PR, Brasil. | en_US |
| Subject | Tissue Engineering | en_US |
| Subject | Transplants | en_US |
| Subject | Decellularized Tissues | en_US |
| Subject | Biocompatible Materials | en_US |
| Subject | Stem Cells | en_US |
| Subject | Macrophages | en_US |
| Subject in Spanish | Ingeniería de Tejidos | en_US |
| Subject in Spanish | Trasplantes | en_US |
| Subject in Spanish | Acellular Dermis | en_US |
| Subject in Spanish | Materiales Biocompatibles | en_US |
| Subject in Spanish | Células Madre | en_US |
| Subject in French | Ingénierie tissulaire | en_US |
| Subject in French | Derme acellulaire | en_US |
| Subject in French | Matériaux biocompatibles | en_US |
| Subject in French | Cellules souches | en_US |
| Subject in French | Macrophages | en_US |
| DeCS | Engenharia Tecidual | en_US |
| DeCS | Transplantes | en_US |
| DeCS | Derme Acelular | en_US |
| DeCS | Biomateriais | en_US |
| DeCS | Células-Tronco | en_US |
| DeCS | Macrófagos | en_US |
