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| Autor | Macedo, Priscila Marques de | |
| Autor | Benko, Lorena Macedo Pestana | |
| Autor | Falcão, Eduardo Mastrangelo Marinho | |
| Autor | Nosanchuk, Joshua D. | |
| Autor | Almeida-Paes, Rodrigo | |
| Autor | Valle, Antonio Carlos Francesconi do | |
| Fecha de acceso | 2023-08-24T19:44:09Z | |
| Fecha de disponibilización | 2023-08-24T19:44:09Z | |
| Fecha de publicación | 2023 | |
| Referencia | MACEDO, Priscila Marques de et al. COVID-19 in patients with paracoccidioidomycosis. v. 17, n. 5, p. 1-8, May 2023. | en_US |
| ISSN | 1935-2727 | en_US |
| URI | https://www.arca.fiocruz.br/handle/icict/60218 | |
| Promoción | This work was supported in part by Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro [FAPERJ E-26/211.430/2021] to PMdM. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | en_US |
| Idioma | eng | en_US |
| Editor | Public Library of Science | en_US |
| Derechos de autor | open access | en_US |
| Título | COVID-19 in patients with paracoccidioidomycosis | en_US |
| Tipo del documento | Article | en_US |
| DOI | 10.1371/journal.pntd.0011322 | |
| Resumen en Inglés | Introduction: In 2020, we reported the first patient with concomitant COVID-19 and paracoccidioidomycosis (PCM). Since then, no other cases have been recorded in the literature. We aim to update information on the occurrence of COVID-19 in patients with PCM followed at a reference center for infectious diseases at Rio de Janeiro, Brazil. Methods: We reviewed the medical records from patients diagnosed with PCM who presented with clinical symptoms, radiological findings, and/or laboratory diagnosis of COVID-19 at any time during their acute or follow-up care. The clinical profiles of these patients were described. Results: Between March 2020 and September 2022, we identified six individuals with COVID-19 among the 117 patients with PCM evaluated. The median age was 38 years and the male to female ratio 2:1. Most patients (n = 5) presented for evaluation due to acute PCM. The severity of COVID-19 ranged from mild to severe in acute PCM and only the single patient with chronic PCM died. Conclusions: There is a range of disease severity in COVID-19 and PCM co-infection and concomitant disease may represent a severe association, especially in the chronic type of the mycosis with pulmonary involvement. As COVID-19 and chronic PCM share similar clinical aspects and PCM is neglected, it is probable that COVID-19 has been hampering simultaneous PCM diagnosis, which can explain the absence of new co-infection reports. With the continued persistence of COVID-19 globally, these findings further suggest that more attention by providers is necessary to identify co-infections with Paracoccidioides. | en_US |
| Afiliación | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Laboratory of Clinical Research on Infectious Dermatology. Rio de Janeiro, RJ, Brazil. | en_US |
| Afiliación | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Laboratory of Clinical Research on Infectious Dermatology. Rio de Janeiro, RJ, Brazil. | en_US |
| Afiliación | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Laboratory of Clinical Research on Infectious Dermatology. Rio de Janeiro, RJ, Brazil. | en_US |
| Afiliación | Departments of Medicine and Microbiology & Immunology. Albert Einstein College of Medicine. Bronx, New York, USA. | en_US |
| Afiliación | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Mycology Laboratory. Rio de Janeiro, RJ, Brazil. | en_US |
| Afiliación | Oswaldo Cruz Foundation. Evandro Chagas National Institute of Infectious Diseases. Laboratory of Clinical Research on Infectious Dermatology. Rio de Janeiro, RJ, Brazil. | en_US |
| Palavras clave en Inglês | COVID-19 | en_US |
| Palavras clave en Inglês | Paracoccidioidomycosis | en_US |
| Palavras clave en Inglês | Patients | en_US |
| Palavras clave en Inglês | Pandemic | en_US |
| e-ISSN | 1935-2735 |
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INI - Artigos de Periódicos [3646]