Author | Reis, Erika Cardoso dos | |
Author | Monteiro, Elma Lúcia de Freitas | |
Author | Meneguci, Joilson | |
Author | Rodrigues, Phillipe | |
Author | Palma, Alexandre | |
Author | Virtuoso Junior, Jair Sindra | |
Author | Passos, Sonia Regina Lambert | |
Author | Santos, Maria Angelica Borges dos | |
Access date | 2023-10-29T16:05:42Z | |
Available date | 2023-10-29T16:05:42Z | |
Document date | 2023 | |
Citation | REIS, Erika Cardoso dos et al. Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database. BMC Public Health, v. 23, p. 1-11, Aug. 2023. | en_US |
ISSN | 1471-2458 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/60982 | |
Sponsorship | This study was financed in part by the Pan American Health Organization (PAHO) and the Coordination for the Improvement of Higher Education Personnel (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES) - Finance Code 001. | en_US |
Language | eng | en_US |
Publisher | BioMed Central | en_US |
Rights | open access | en_US |
Title | Body mass index and sex differences for mortality in hospitalized COVID-19 patients: a path analysis using a brazilian national database | en_US |
Type | Article | en_US |
DOI | 10.1186/s12889-023-16218-1 | |
Abstract | Previous studies have shown that associations between obesity and other comorbidities favor worse outcomes in COVID-19. However, it is not clear how these factors interrelate and whether effects on men and women differ. We conducted an observational, cross-sectional study using a national COVID-19 inpatient database. We studied differences in direct and indirect effects of obesity and comorbidities according to sex and body mass index (BMI) categories in hospitalized COVID-19 patients in Brazil using path analysis models and logistic regression. For men, path analysis showed a direct association between BMI and death and a negative correlation of death and chronic cardiovascular disease (CCD). For women, the association of BMI and death was indirect, mediated by admission to the ICU and comorbidities and association with CCD was non-significant. In the logistic regression analyses, there was a positive association between death and BMI, age, diabetes mellitus, kidney and lung diseases and ICU admission. We highlight the need to consider the distinct impact of obesity and sex on COVID-19, of monitoring of BMI and of the design for specific male-targeted approaches to manage obesity. | en_US |
Affilliation | Universidade Federal de Ouro Preto. Escola de Nutrição, Departamento de Nutrição Clínica e Social. Ouro Preto, MG, Brazil. | en_US |
Affilliation | Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil. | en_US |
Affilliation | Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil. | en_US |
Affilliation | Universidade Federal do Rio de Janeiro. Escola de Educação Física e Desportos. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil. | en_US |
Affilliation | Universidade Federal do Triângulo Mineiro. Programa de Pós Graduação em Atenção à Saúde. Uberaba, MG, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brazil. | en_US |
Subject | COVID-19 | en_US |
Subject | Obesity | en_US |
Subject | Pandemics | en_US |
e-ISSN | 1471-2458 | |