Author | Cristovão-Silva, Ana Catarina | |
Author | Brelaz-de-Castro, Maria Carolina Accioly | |
Author | Hernandes, Marcelo Zaldini | |
Author | Pereira, Valéria Rêgo Alves | |
Access date | 2023-12-11T12:53:41Z | |
Available date | 2023-12-11T12:53:41Z | |
Document date | 2021 | |
Citation | CRISTOVÃO-SILVA, Ana Catarina et al. Chagas disease: immunology of the disease at a glance. Cytokine & Growth Factor Reviews, [S.l.], v. 62, p. 15-22, dez. 2021. | en_US |
ISSN | 1879-0305 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/61682 | |
Language | por | en_US |
Rights | open access | en_US |
MeSH | Adaptive Immunity | en_US |
MeSH | Chagas Disease* | en_US |
MeSH | Cytokines | en_US |
MeSH | Humans | en_US |
MeSH | Trypanosoma cruzi* | en_US |
Title | Chagas disease: Immunology of the disease at a glance | en_US |
Type | Article | en_US |
DOI | 10.1016/j.cytogfr.2021.10.001 | |
Abstract | Chagas disease is an important neglected disease that affects 6-7 million people worldwide. The disease has two phases: acute and chronic, in which there are different clinical symptoms. Controlling the infection depends on innate and acquired immune responses, which are activated during the initial infection and are critical for host survival. Furthermore, the immune system plays an important role in the therapeutic success. Here we summarize the importance of the immune system cytokines in the pathology outcome, as well as in the treatment. | en_US |
Affilliation | Universidade Federal de Pernambuco. Centro de Biociências. Recife, PE, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil. | en_US |
Affilliation | Universidade de Pernambuco. Departamento de Ciências Farmacêuticas. Recife, PE, Brasil. | en_US |
Affilliation | Universidade Federal de Pernambuco. Centro de Biociências. Recife, PE, Brasil. | en_US |
Subject | Benzonidazole | en_US |
Subject | Cytokines; Immune system | en_US |
Subject | Neglected disease | en_US |
Subject | Treatment | en_US |
Subject | Trypanosoma cruzi | en_US |