| Author | Torres, Thiago S. | |
| Author | Teixeira, Sylvia L. M. | |
| Author | Hoagland, Brenda | |
| Author | Konda, Kelika A. | |
| Author | Derrico, Monica | |
| Author | Moreira, Ronaldo I. | |
| Author | Guanira, Juan V. | |
| Author | Benedetti, Marcos | |
| Author | Nazer, Sandro | |
| Author | Calvo, Gino M. | |
| Author | Vargas, Silver | |
| Author | Benites, Carlos | |
| Author | Bigolin, Álisson | |
| Author | Alonso Neto, José Boullosa | |
| Author | Farias, Alessandro | |
| Author | Lacerda, Marcos Vinícius Guimarães | |
| Author | Silva, Daila Alena Raenck | |
| Author | Paz, Leidijany Costa | |
| Author | Madruga, José Valdez | |
| Author | Flores, Hector Javier Salvatierra | |
| Author | Boluarte, Ginjaylan Prada | |
| Author | Tamayo, Cesar Vidal Osco | |
| Author | Antezana, Hardy Teresa Castro | |
| Author | Pimenta, M. Cristina | |
| Author | Bórquez, Annick | |
| Author | Luz, Paula M. | |
| Author | Grinsztejn, Beatriz | |
| Author | Szwarcwald, Celia Landmann | |
| Author | Cáceres, Carlos F. | |
| Author | Veloso, Valdiléa G. | |
| Access date | 2024-01-09T12:32:02Z | |
| Available date | 2024-01-09T12:32:02Z | |
| Document date | 2023 | |
| Citation | TORRES, Thiago S. et al. Recent HIV infection and annualized HIV incidence rates among sexual and gender minorities in Brazil and Peru (ImPrEP seroincidence study): a cross-sectional, multicenter study. Lancet Regional Health, v. 28, p. 1-12, Dec. 2023. | en_US |
| ISSN | 2667-193X | |
| URI | https://www.arca.fiocruz.br/handle/icict/62116 | |
| Language | eng | en_US |
| Publisher | Elsevier | en_US |
| Rights | open access | |
| Title | Recent HIV infection and annualized HIV incidence rates among sexual and gender minorities in Brazil and Peru (ImPrEP seroincidence study): a cross-sectional, multicenter study | en_US |
| Type | Article | |
| DOI | 10.1016/j.lana.2023.100642 | |
| Abstract | Background: HIV incidence estimation is critical for monitoring the HIV epidemic dynamics and the effectiveness of public health prevention interventions. We aimed to identify sexual and gender minorities (SGM) with recent HIV infections, factors associated with recent HIV infection, and to estimate annualised HIV incidence rates. Methods: Cross-sectional multicentre study in HIV testing services in Brazil and Peru (15 cities). Inclusion criteria: 18+ years, SGM assigned male at birth, not using pre-/post-exposure prophylaxis. We identified recent HIV infection using the Maxim HIV-1 LAg-Avidity EIA assay as part of a recent infection testing algorithm (RITA). Annualized HIV incidence was calculated using the UNAIDS/WHO incidence estimator tool. Multivariable logistic regression models were used to estimate factors associated with recent HIV infection. Trial registration: NCT05674682. Findings: From 31-Jan-2021 to 29-May-2022, 6899 individuals participated [Brazil: 4586 (66.5%); Peru: 2313 (33.5%)]; 5946 (86.2%) cisgender men, 751 (10.9%) transgender women and 202 (2.9%) non-binary/gender diverse. Median age was 27 (IQR: 23-34) years. HIV prevalence was 11.4% (N = 784/6899); 137 (2.0%) SGM were identified with recent HIV infection. The overall annualized HIV incidence rate was 3.88% (95% CI: 2.86-4.87); Brazil: 2.62% (95% CI: 1.78-3.43); Peru: 6.69% (95% CI: 4.62-8.69). Participants aged 18-24 years had higher odds of recent HIV infection compared to those aged 30+ years in both countries. Interpretation: Our results highlight the significant burden of HIV epidemic among SGM in large urban centres of Brazil and Peru. Public health policies and interventions to increase access to effective HIV prevention methods such as PrEP are urgently needed in Latin America. Funding: Unitaid, WHO Switzerland), Ministry of Health from Brazil and Peru. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Laboratory of AIDS & Molecular Immunology. Rio de Janeiro, RJ, Brazil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidad Peruana Cayetano Heredia. Centro de Investigaciones Interdisciplinaria en Sexualidad SIDA y Sociedad. Lima, Peru. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidad Peruana Cayetano Heredia. Centro de Investigaciones Interdisciplinaria en Sexualidad SIDA y Sociedad. Lima, Peru. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidad Peruana Cayetano Heredia. Centro de Investigaciones Interdisciplinaria en Sexualidad SIDA y Sociedad. Lima, Peru. | |
| Affilliation | Universidad Peruana Cayetano Heredia. Centro de Investigaciones Interdisciplinaria en Sexualidad SIDA y Sociedad. Lima, Peru. | |
| Affilliation | Ministério de Salud. National Program for HIV/STI/Viral Hepatitis Prevention and Control. Lima, Peru. | |
| Affilliation | Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Departamento de HIV/Aids, Tuberculose, Hepatites Virais e Infecções Sexualmente Transmissíveis. Brasília, DF, Brasil. | |
| Affilliation | Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Departamento de HIV/Aids, Tuberculose, Hepatites Virais e Infecções Sexualmente Transmissíveis. Brasília, DF, Brasil. | |
| Affilliation | Centro Especializado em Diagnóstico, Assistência e Pesquisa. Salvador, BA, Brasil. | |
| Affilliation | Fundação de Medicina Tropical Doutor Heitor Vieira Dourado. Manaus, AM, Brasil. | |
| Affilliation | Secretaria Municipal de Saúde de Porto Alegre. Centro de Testagem e Aconselhamento Santa Marta. Porto Alegre, RS, Brasil. | |
| Affilliation | Hospital Dia Asa Sul. Brasília, DF, Brasil. | |
| Affilliation | Centro de Referência e Treinamento em DST/AIDS-CRT-SP. São Paulo, SP, Brasil. | |
| Affilliation | Centro de Salud Alberto Barton. Callao, Peru. | |
| Affilliation | Centro Materno Infantil Tahuantinsuyo Bajo. Independencia, Peru. | |
| Affilliation | Centro Materno Infantil Tahuantinsuyo Bajo. Independencia, Peru. | |
| Affilliation | Hospital Santa Maria del Socorro. Ica, Peru. | |
| Affilliation | Ministério da Saúde. Secretaria de Vigilância em Saúde e Ambiente. Departamento de HIV/Aids, Tuberculose, Hepatites Virais e Infecções Sexualmente Transmissíveis. Brasília, DF, Brasil. | |
| Affilliation | Centro de Salud Alberto Barton. Callao, Peru / University of California. Division of Infectious Diseases and Global Public Health. San Diego, USA. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Centro Materno Infantil Tahuantinsuyo Bajo. Independencia, Peru / Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Rio de Janeiro, RJ, Brasil. | |
| Affilliation | Universidad Peruana Cayetano Heredia. Centro de Investigaciones Interdisciplinaria en Sexualidad, SIDA y Sociedad. Lima, Peru. | |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | |
| Subject | HIV Incidence Rate | en_US |
| Subject | HIV Seroincidence | en_US |
| Subject | HIV Recency | en_US |
| Subject | Sexual and Gender Minorities | en_US |
| Subject | HIV | en_US |
| Subject | Latin America | en_US |
| Subject | Public Health | en_US |
| e-ISSN | 2667-193X | |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
| xmlui.metadata.dc.subject.ods | 10 Redução das desigualdades | |
