| Author | Araújo, Aurélio A. | |
| Author | Codeço, Cláudia | |
| Author | Freitas, Dayvison Francis Saraiva | |
| Author | Macedo, Priscila M. de | |
| Author | Pereira, Sandro A. | |
| Author | Gremião, Isabella D. F. | |
| Author | Coelho, Flávio Codeço | |
| Access date | 2024-02-20T23:41:59Z | |
| Available date | 2024-02-20T23:41:59Z | |
| Document date | 2023 | |
| Citation | ARAÚJO, Aurélio A. et al. Mathematical model of the dynamics of transmission and control of sporotrichosis in domestic cats. Plos One, v. 18, n. 2, p. 1-14, Feb. 2023. | en_US |
| ISSN | 1932-6203 | |
| URI | https://www.arca.fiocruz.br/handle/icict/62707 | |
| Language | eng | en_US |
| Publisher | Public Library of Science | en_US |
| Rights | open access | en_US |
| Title | Mathematical model of the dynamics of transmission and control of sporotrichosis in domestic cats | en_US |
| Type | Article | |
| DOI | 10.1371/journal.pone.0272672 | |
| Abstract | Sporotrichosis is a subcutaneous mycosis with a global distribution, also known as “rose gardener’s disease”. Brazil is experiencing a rapid spread of the zoonotic transmission of of Sporothrix brasiliensis, the main etiological agent of this disease in this country, affecting domestic felines. Cost-effective interventions need to be developed to control this emergent public health problem. To allow for the comparison of alternative control strategies, we propose in this paper, a mathematical model representing the transmission of S. brasiliensis among cats, stratified by age and sex. Analytical properties of the model are derived and simulations show possible strategies for reducing the endemic levels of the disease in the cat population, with a positive impact on human health. The scenarios included mass treatment of infected cats and mass implementation of contact reduction practices, such as neutering. The results indicate that mass treatment can reduce substantially the disease prevalence, and this effect is potentialized when combined with neutering or other contactreduction interventions. On the other hand, contact-reduction methods alone are not sufficient to reduce prevalence. | en_US |
| Affilliation | Oswaldo Cruz Foundation. Presidency. Computational and Systems Biology. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Oswaldo Cruz Foundation. Presidency. Scientific Computing Program. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
| Affilliation | Oswaldo Cruz Foundation. Presidency. Scientific Computing Program. Rio de Janeiro, RJ, Brazil. | en_US |
| Affilliation | Oswaldo Cruz Foundation. Presidency. Computational and Systems Biology. Rio de Janeiro, RJ, Brazil / Fundação Getulio Vargas. School of Applied Mathematics. Rio de Janeiro, RJ, Brasil / University of Geneva. Institute of Global Health. Geneva, Switzerland. | en_US |
| Subject | Sporotrichosis | en_US |
| Subject | Domestic Cats | en_US |
| Subject | Brazil | en_US |
| Subject | Sporothrix brasiliensis | en_US |
| e-ISSN | 1932-6203 | |
